Results 31 to 40 of about 93,276 (264)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Silicon Isotope Geochemistry: Fractionation Linked to Silicon Complexations and Its Geological Applications

Molecules, 2019
The fundamental advances in silicon isotope geochemistry have been systematically demonstrated in this work. Firstly, the continuous modifications in analytical approaches and the silicon isotope variations in major reservoirs and geological processes ...
Wei Wang, Hai-Zhen Wei, Shao-Yong Jiang, Xi Liu, Fang Lei, Yi-Bo Lin, Yao Zhao   +6 more
doaj   +1 more source

Carbon isotope effects in the sorption of chlorinated ethenes on biochar and activated carbon

Heliyon, 2023
As an alternative to activated carbon, biochar is a promising, environmentally friendly sorbent that can be used to remove organic groundwater pollutants, such as chlorinated ethenes (CEs).
Simon Leitner, Fridjof Sobanski, Gerhard Soja, Katharina Keiblinger, Christine Stumpp, Andrea Watzinger   +5 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Barium isotopic fractionation during strong weathering of basalt in a tropical climate

Environment International, 2020
Barium (Ba) is an element which is toxic to humans, plants, and animals. Deciphering the geochemical behavior of Ba in soils is fundamental for assessing the potentials risks posed by Ba. Ba isotopes are a potentially robust tracer of Ba in soils.
Yingzeng Gong, Zhen Zeng, Wenhan Cheng, Ying Lu, Lili Zhang, Huimin Yu, Fang Huang   +6 more
doaj   +1 more source

Effects of Temperature and Chemical Speciation of Mineral Elements on PM10 Formation during Zhundong Coal Combustion

Energies, 2022
Particulate matter (PM) pollution from coal combustion is a leading contributor to the influence of atmospheric visibility, photochemical smog, and even global climate.
Qiaoqun Sun, Zhiqi Zhao, Shizhang Wang, Yu Zhang, Yaodong Da, Heming Dong, Jiwang Wen, Qian Du, Jianmin Gao   +8 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Qualitative parameters of sugarcane silages treated with urea and calcium oxide

Semina: Ciências Agrárias, 2015
The objective was to evaluate the fermentation parameters, chemical composition and fractionation of carbohydrates of sugarcane silages treated with urea and calcium oxide (CaO).
Susi Cristina dos Santos Guimarães Martins , Gleidson Giordano Pinto Carvalho , Aureliano José Vieira Pires , Robério Rodrigues Silva , Laudi Cunha Leite , Fabiano Matos Pereira , Álvaro Diego Soares Mota , Isis Miranda Carvalho Nicory, Cláudia Horne da Cruz   +8 more
doaj   +1 more source