Results 81 to 90 of about 93,276 (264)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Oxygen Isotope Fractionation in the Martian Atmosphere Induced by CO2 Photolysis and O3 Formation

The Planetary Science Journal
The enrichment of heavy isotopes of volatile elements in the Martian atmosphere indicates that Mars lost a large portion of its atmosphere through escape to space. Recent atmospheric measurements by the ExoMars Trace Gas Orbiter (TGO) have suggested that
Tatsuya Yoshida, Shohei Aoki, Hiromu Nakagawa, Naoki Terada, Juan Alday, Akinori Hasebe, Yuki Nakamura, Shungo Koyama, Shotaro Sakai, Ryoya Sakata, Ann Carine Vandaele   +10 more
doaj   +1 more source

Ultra-violet absorption cross sections of isotopically substituted nitrous oxide species: ¹⁴N¹⁴NO, ¹⁵N¹⁴NO, ¹⁴N¹⁵NO and ¹⁵N¹⁵NO [PDF]

Atmospheric Chemistry and Physics, 2004
The isotopically substituted nitrous oxide species 14N14NO, 15N14NO, 14N15NO and 15N15NO were investigated by ultra-violet (UV) absorption spectroscopy. High precision cross sections were obtained for the wavelength range 181 to 218nm at temperatures of ...
P. von Hessberg, J. Kaiser, J. Kaiser, M. B. Enghoff, C. A. McLinden, S. L. Sorensen, T. Röckmann, M. S. Johnson   +7 more
doaj  

Correction: Salazar-Cubillas, K.C.; Dickhoefer, U. Evaluating the Protein Value of Fresh Tropical Forage Grasses and Forage Legumes Using In Vitro and Chemical Fractionation Methods. Animals 2021, 11, 2853. [PDF]

Animals (Basel), 2022
Salazar-Cubillas KC, Dickhoefer U.
europepmc   +1 more source

Extreme Crustal Fractionation in a Proterozoic Chemical Hotspot

Journal of Petrology
Abstract The distribution of mineral systems is heterogeneous over space and time, reflecting transient element enrichment within Earth’s evolving crust. Australian Proterozoic rocks host some of the world’s largest ore deposits, including the Broken Hill Pb–Zn–Ag deposit within the Curnamona Province, and the Olympic Dam Cu–U–Au–Ag ...
Janne Liebmann, Bryant Ware, Christopher Kirkland, David Mole, Geoffrey Fraser, Brandon Mahan, Ashlea Wainwright, Roland Maas   +7 more
openaire   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

AN EVOLUTION FROM PRETREATMENT TO FRACTIONATION WILL ENABLE SUCCESSFUL DEVELOPMENT OF THE INTEGRATED BIOREFINERY

BioResources, 2010
The current state of biorefinery development is focused almost entirely on the production of fuel ethanol. However, an ethanol-centric approach misses the crucial example set by the petrochemical industry.
Joseph J. Bozell
doaj  

Fractionation of Irradiated Cholesterol: Chemical Observations.

Experimental Biology and Medicine, 1926
One of us recently reported1 that cholesterol, as a result of exposure in air to light from the mercury-vapor quartz lamp, reacted differently from the untreated cholesterol towards a reagent consisting of aniline and concentrated hydrochloric acid. With the aid of this color reaction, fractionation of irradiated cholesterol was undertaken.
M. J. Shear, B. Kramer
openaire   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source