Novel Type III Polyketide Synthases Biosynthesize Methylated Polyketides in Mycobacterium marinum
Mycobacterial pathogenesis is hallmarked by lipidic polyketides that decorate the cell envelope and mediate infection. However, factors mediating persistence remain largely unknown.
Amreesh Parvez +5 more
doaj +1 more source
Safety and efficacy of the feed additives 2-acetylfuran [13.054] and 2-pentylfuran [13.059] belonging to chemical group 14 for animal species (FEFANA asbl). [PDF]
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +22 more
europepmc +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Mining activities produce a significant amount of gold mine tailings (GMT) rich in rare earth elements. Despite this, little information is available regarding the effective extraction of these precious elements from GMT. We describe a novel strategy for
Hoda Fereydouni +2 more
doaj +1 more source
Safety of feed additives consisting of β-damascone [07.083] and (E)-β-damascone [07.224] belonging to chemical group 8 for use in all animal species (FEFANA asbl). [PDF]
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +20 more
europepmc +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
The present work reports the distribution of pollutants in the Madrid city and province from 22 monitoring stations during 2010 to 2017. Statistical tools were used to interpret and model air pollution data.
David Núñez-Alonso +3 more
doaj +1 more source
Chemical Group Profiling, In Vitro and In Silico Evaluation of Aristolochia ringens on α-Amylase and α-Glucosidase Activity. [PDF]
Ahmad JB, Ajani EO, Sabiu S.
europepmc +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Antea Group Archeologie 2016/54
In opdracht van de gemeente Waalwijk heeft Antea Group in 2016 een archeologisch bureauonderzoek uitgevoerd naar de beschikbare archeologische gegevens met betrekking tot de Havenzone ten zuiden van de Rijksweg A59 te Waalwijk.
Koopmanschap, Dr. H.J.L.C. (Antea Group)
core +1 more source

