Results 91 to 100 of about 1,579,641 (309)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Synthesis and Characterization of Thymine-15N2
Journal of Isotopes, 2016 A novel and mild synthesis method of thymine-15N2 was designed. Ethyl formate and ethyl propionate as raw materials, the intermediate ethyl 2-formylpropionate was condensed under sodium metal, the target compound thymine-15N2 was obtained by condensation
XU Jian-fei +3 more
doaj +1 more source
Field Evaluations of Herbicides on Vegetable, Small Fruit, and Ornamental Crops, 2000, 2001, & 2002 [PDF]
, 2004 Field evaluations of herbicides provide the chemical industry, governmental agencies, such as IR-4, and the Arkansas Agricultural Experiment Station with an evaluation of herbicide performance on small fruit, vegetable, and ornamental crops grown under ...
Lovelace, Mike L. +3 more
core +2 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Journal of Electrochemical Science and Engineering, 2019 In this work, NiCo2O4 nanoparticles with enhanced supercapacitive performance have been successfully synthesized via a facile sol-gel method and subsequent calcination in air. The morphology and composition of as-prepared samples were characterized using
Yong Zhang +10 more
doaj +1 more source
Allocative efficiency measurement revisited: Do we really need input prices? [PDF]
The traditional approach to measuring allocative efficiency is based on input prices, which are rarely known at the firm level. This paper proposes a new approach to measure allocative efficiency which is based on the output-oriented distance to the ...
Badunenko, Oleg +2 more
core +3 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The Lautenberg Act: Chemical Safety Overhaul of the Toxic Substances Control Act [PDF]
, 2016 On June 22, 2016, President Obama signed the Frank Lautenberg Chemical Safety for the 21st Century Act (Lautenberg Act), a landmark bipartisan compromise legislation designed to overhaul the Toxic Substances Control Act (TSCA).
Rosen, Alyssa S.
core +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Advanced Co3O4 interlayer as an efficient polysulfide barrier for high-performance Li-S batteries
International Journal of Electrochemical Science, 2019 In this paper, Co3O4 powders were firstly prepared via hydrothermal reaction. Then, Co3O4 powder was used as interlayer and applied into Li-S battery.
Li Xiao-qingl, Ma Yu-bo, Tang Cheng-li
doaj +1 more source