Results 71 to 80 of about 8,448,076 (261)

Probing the Curing Reaction of HTPB Propellant with Low-Field NMR

open access: yesAerospace
Hydroxyl-terminated polybutadiene (HTPB) propellants are widely used in aerospace applications owing to their excellent mechanical performance and storage stability, which are primarily governed by the crosslinked network formed during curing ...
Mengrui Yu   +7 more
doaj   +1 more source

The study on catalytic performance of CuO/CexZr1-xO2 catalyst in carbon monoxide oxidation

open access: yes上海师范大学学报. 自然科学版, 2017
A series of CuO/CexZr1-xO2 samples were prepared by incipient-wetness impregnation method with CexZr1-xO2 used as the catalyst carrier which was synthesized by co-precipitation method.The influences of the mass ratio of CeO2:ZrO2 and CuO loading were ...
Huang Jinhua, Ye Liping, Li Shuai
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Industry facts and figures

open access: yes, 2009
+73hlm ...
INDUSTRY FACTS AND
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Effect of Substrate Concentration (Glucose) on Ethanol Fermentation Continue with Immobilized Fixed Bed Fermenter for 2/3 Mesh Pumice Anchoring Size [PDF]

open access: yesE3S Web of Conferences
The need for ethanol which is increasing at all times demands development related to ethanol production, especially those produced through the fermentation process both development in terms of raw materials and processes.
Nabila Baharudin Fatwa   +3 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

EVOH functionalized PE battery separator as the porous substrate for TFC organic solvent nanofiltration membranes

open access: yesAdvanced Membranes
Scholarly discourse surrounding the thin film composite organic solvent nanofiltration (TFC OSN) membrane field has largely been dominated by focusing on the optimization of the selective layer.
Guoke Zhao   +6 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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