Results 51 to 60 of about 8,448,076 (261)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Polymer-Supported Raney Nickel Catalysts for Sustainable Reduction Reactions

Molecules, 2016
Green is the future of chemistry. Catalysts with high selectivity are the key to green chemistry. Polymer-supported Raney catalysts have been found to have outstanding performance in the clean preparation of some chemicals.
Haibin Jiang, Shuliang Lu, Xiaohong Zhang, Wei Dai, Jinliang Qiao   +4 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Activating Progressive Sn2+ Nucleation by Micellar Structure Electrolyte for Dead-Sn-Free Aqueous Batteries

Nano-Micro Letters
Highlights Nanoscale spatial confinement of Sn2+ ions is realized in SnSO4 electrolyte by strategically dictating spontaneous assembly of nanomicelles with amphipathic sulfolane.
Xiaojia Lan, Zhaoyu Zhang, Yuekai Lin, Wencheng Du, Yufei Zhang, Minghui Ye, Zhipeng Wen, Yongchao Tang, Xiaoqing Liu, Cheng Chao Li   +9 more
doaj   +1 more source

Isolation of Sulfuretin and Butin from Rhus verniciflua Stokes Using Medium-pressure Liquid Chromatography and their Tyrosinase Inhibitory Effects

BioResources, 2015
The aim of this study was to separate antityrosinase compounds of the ethyl acetate fraction from Rhus verniciflua Stokes using medium pressure liquid chromatography.
Hongxia Chen, Chengzhang Wang, Jianzhong Ye, Hao Zhou, Ran Tao   +4 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Preparation and Characterization of Urushiol Methylene Acetal Derivatives with Various Degrees of Unsaturation in Alkyl Side Chain

International Journal of Polymer Science, 2015
Preparation of urushiol derivatives was carried out in response to the drug industry’s increasing demand for new synthetic anticancer agents. Urushiol methylene acetal derivatives were synthesized in high yields by reaction of urushiol with methylene ...
Chengzhang Wang, Yuanfeng He, Hao Zhou, Ran Tao, Hongxia Chen, Jianzhong Ye, Yusi Zhang   +6 more
doaj   +1 more source

Synthesis of Spherical Silver-coated Li4Ti5O12 Anode Material by a Sol-Gel-assisted Hydrothermal Method

Nanoscale Research Letters, 2017
ᅟ Ag-coated spherical Li4Ti5O12 composite was successfully synthesized via a sol-gel-assisted hydrothermal method using an ethylene glycol and silver nitrate mixture as the precursor, and the influence of the Ag coating contents on the electrochemical ...
Jun Li, Si Huang, Shuaijun Xu, Lifang Lan, Lu Lu, Shaofang Li   +5 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source