Results 41 to 50 of about 8,448,076 (261)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
CO2 methanation over TiO2-Al2O3 binary oxides supported Ru catalysts
TiO2 modified Al2O3 binary oxide was prepared by a wet-impregnation method and used as the support for ruthenium catalyst. The catalytic performance of Ru/TiO2-Al2O3 catalyst in CO2 methanation reaction was investigated.
Su, Xiong +5 more
core +1 more source
Chemical looping gasification (CLG) provides a novel approach to dispose the sewage sludge. In order to improve the reactivity of the calcined copper slag, NiO modification is considered as one of the good solutions.
Huo, Ruiqiang +7 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
A CFD model for predicting the heat transfer in the industrial scale packed bed
Compared to the traditional lumped-parameter model, computational fluid dynamics (CFD) attracted more attentions due to facilitating more accurate reactor design and optimization methods when analyzing the heat transfer in the industrial packed bed. Here,
Xiaodong Wang +9 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Prof. Zhu Yajie, EditorFrom Preface: Zhu Ya-jie, Conference Chairman; World petroleum and natural gas reserves from long term consideration are, however finite, although it is still too early to give a confirmatory statement to predict the years of oil ...
Yajie, Zhu
core
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Aligned Chemically Etched Silver Nanowire Monolayer as Surface-Enhanced Raman Scattering Substrates
Silver nanowires (AgNWs) were chemically etched to significantly increase the surface roughness and then self-assembled on the liquid/gas interfaces via the interfacial assembly method to obtain aligned chemically etched silver nanowire films.
Jianchao Wang +5 more
doaj +1 more source

