Results 41 to 50 of about 9,039,490 (311)
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Frontiers in ChemistryOxidative stress is implicated in numerous pathological processes. Developing efficient, safe small-molecule antioxidants is of great medicinal interest. In this work, ten new indole derivatives bearing a thiosemicarbazide moiety (4a–4j) were synthesized
Tao Wang +7 more
doaj +1 more source
Research on Population Trends and Optimal Allocation of Urban and Rural Public Resources in Luzhou City Based on Multi source Remote Sensing Data [PDF]
SHS Web of ConferencesPopulation is an important basis for land and resource planning, and optimising the allocation of urban and rural public resources is conducive to the development of the regional economy and the protection of the regional ecological environment. Existing
Bing Xiao +6 more
doaj +1 more source
, 2020 In this paper, the solid waste desulfurization gypsum produced by coal-fired power plants was used as a raw material to prepare calcium sulfate whiskers with high application prospects.
Li, Qiang, Liu, Fuli, Gao, Jing
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Fabrication of Ordered Nanopattern by using ABC Triblock Copolymer with Salt in Toluene
Nanoscale Research Letters, 2017 Ordered nanopatterns of triblock copolymer polystyrene-block-poly(2-vinylpyridine)-block- poly (ethylene oxide)(PS-b-P2VP-b-PEO) have been achieved by the addition of lithium chloride (LiCl).
Hailiang Huang +7 more
doaj +1 more source
Experimental infection of indigenous North African goats with goatpox virus
Acta Veterinaria Scandinavica, 2021 Background Goatpox is a viral disease caused by infection with goatpox virus (GTPV) of the genus Capripoxvirus, Poxviridae family. Capripoxviruses cause serious disease to livestock and contribute to huge economic losses. Goatpox and sheeppox are endemic
Jihane Hamdi +7 more
doaj +1 more source
Results in Chemistry, 2021 The aim of this study was the evaluation of the safety parameters: Time to Maximum Rate under adiabatic conditions (TMRad) and self-accelerating decomposition temperature (SADT) for 3-bromo-1-(3,5-dichloropyridin-2-yl)-4,5-dihydro-1H-pyrazole −5 ...
Yun-Bo Cong +6 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source