Results 61 to 70 of about 8,448,076 (261)

Application of deep learning-based video AI analysis in coal mine safety monitoring

open access: yesDiscover Computing
Conventional safety monitoring methods are increasingly inadequate for the complex conditions of modern coal mines. This study introduces a safety monitoring framework based on an enhanced YOLO model, specifically adapted for underground environments ...
Gang Guo   +7 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Implications for Energy Innovation from the chemical industry [PDF]

open access: yes
The history of innovation in the chemical industry offers many insights for accelerating energy innovation. In this chapter, we begin by laying out the early history of the chemical industry for an overview of the role innovation has played in its ...
Alfonso Gambardella, Ashish Arora
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Industry : For A Better Life

open access: yes, 2007
+52hlm ...
INDUSTRY
core  

Construction of hyperthermostable d‐allulose 3‐epimerase from Arthrobacter globiformis M30 using the sequence information from Arthrobacter psychrolactophilus

open access: yesFEBS Open Bio
d‐Allulose is one of the rare monosaccharides and is considered as a safe ingredient in foods. It can be enzymatically produced from d‐fructose by the enzyme d‐allulose 3‐epimerase.
Kensaku Shimada   +3 more
doaj   +1 more source

High-performance and recyclable epoxy resins based on fully bio-based hardeners containing Schiff base structures

open access: yesRoyal Society Open Science
The development of recyclable bio-based epoxy resins has been the focus of research nowadays, particularly in light of increasing environmental concerns and the drive for resource recycling.
Ruize Zhang   +7 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Downsizing in German Chemical Manufacturing Industry during the 1990s: Why Small Is Beautiful? [PDF]

open access: yes
German chemical manufacturing industry is marked by two major structural changes during 1992-2004. Firstly, number of firms was ranging extensively: from 676 to 901, while only 96 firms represented balanced panel.
Oleg Badunenko
core  

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