Results 131 to 140 of about 1,579,641 (309)
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Chemicals from Poland : a tempest in a teacup [PDF]
In the early 1980s, the Polish chemical industry got caught up in a battle waged by the European Community's chemical industry to preserve the EC market for itself.
Olechowski, Andrzej
core
Net-zero transition of the global chemical industry with CO2-feedstock by 2050: feasible yet challenging. [PDF]
Green Chem, 2023 Huo J +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Fatty Acids and their Derivatives as Renewable Platform Molecules for the Chemical Industry. [PDF]
Angew Chem Int Ed Engl, 2021 Biermann U +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Implementing precision agriculture in the oil palm industry: a case of oil palm management system (OPAMS) [PDF]
, 2018 Sustainable agriculture slowly replaces the conventional agriculture practice as due to the need of having sustainable agriculture management to address mainly food scarcity issue over the world; and at a micro-level it’s advancement of technological ...
Sam, Thoong Hai
core
Integrated Diagnostic Framework for Process and Sensor Faults in Chemical Industry. [PDF]
Sensors (Basel), 2021 Zhang J, Luo W, Dai Y.
europepmc +1 more source