Results 101 to 110 of about 5,270,569 (356)

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Hydrothermally Synthesized ZnCr- and NiCr-Layered Double Hydroxides as Hydrogen Evolution Photocatalysts

Molecules
The layered double hydroxides (LDHs) of transition metals are of great interest as building blocks for the creation of composite photocatalytic materials for hydrogen production, environmental remediation and other applications. However, the synthesis of
Sergei A. Kurnosenko, Oleg I. Silyukov, Ivan A. Rodionov, Anna S. Baeva, Andrei A. Burov, Alina V. Kulagina, Silvestr S. Novikov, Irina A. Zvereva   +7 more
doaj   +1 more source

Synthesis, Characterization and Copolymerization of N-(phenylamino)maleimide with MMA

E-Journal of Chemistry, 2007
The free radical copolymerization of N-(phenylamino)maleimide (N-PAMI) was carried. The copolymerization with methyl methacrylate (MMA) was performed at 65°C with AIBN as the initiator in THF solvent.
B. L. Hiran, S. N. Paliwal, Jyoti Choudhary, P. R. Choudhary   +3 more
doaj   +1 more source

Mean-field cooperativity in chemical kinetics

, 2011
We consider cooperative reactions and we study the effects of the interaction strength among the system components on the reaction rate, hence realizing a connection between microscopic and macroscopic observables.
A Barra, A Barra, A Marangoni, A Pagnani, Adriano Barra, Aldo Di Biasio, AP Chatterjee, AV Hill, CJ Thompson, D Voet, DJ Amit, E Agliari, E Agliari, EL Margelefsky, Elena Agliari, H Diamant, J Monod, J Wong, JM Cases, JP Changeux, JT Edsall, L Acerenza, PF Cook, Q Cui, R Burioni, Raffaella Burioni, RS Ellis, S Karlin, TL Hill, W Bialek, Y Murase   +30 more
core   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Kinetic Isotope Effect in the Unfolding of a Protein Secondary Structure: Calculations for Beta-Sheet Polyglycine Dimers as a Model

Biomolecules
In the present work, we performed calculations of the kinetic isotope effect (KIE) on H/D, 14N/15N, 16O/18O, and 12C/13C isotopic substitution in the dissociation of beta-sheet polyglycine dimers of different lengths into two monomer chains.
Alexey O. Yanshin, Vitaly G. Kiselev, Alexey V. Baklanov   +2 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

On the multistationarity of chemical reaction networks

, 2019
We present a new conjecture about a necessary condition that a (bio)chemical network has to satisfy for it to exhibit multistationarity. According to a Theorem of Feliu and Wiuf [27, 12], the conjecture is known for strictly monotonic kinetics.
Kaufman, Marcelle, Soulé, Christophe
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Influence of chemical reaction kinetics on electrokinetic remediation modelling results [PDF]

, 2017
A numerical model describing transport of multiple species and chemical reactions during electrokinetic treatment is presented. The transport mechanisms included in the model were electromigration and electroosmosis.
Ceccarini, Alessio, Gomez-Lahoz, Cesar, Iannelli, Renato, Masi, Matteo, Paz-Garcia, Juan Manuel, Villen-Guzman, Maria   +5 more
core