Results 91 to 100 of about 6,188,412 (297)

Synthesis, Characterization and Copolymerization of N-(phenylamino)maleimide with MMA

open access: yesE-Journal of Chemistry, 2007
The free radical copolymerization of N-(phenylamino)maleimide (N-PAMI) was carried. The copolymerization with methyl methacrylate (MMA) was performed at 65°C with AIBN as the initiator in THF solvent.
B. L. Hiran   +3 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Chemical Dynamics, Molecular Energetics, and Kinetics at the Synchrotron [PDF]

open access: yes, 2010
Scientists at the Chemical Dynamics Beamline of the Advanced Light Source in Berkeley are continuously reinventing synchrotron investigations of physical chemistry and chemical physics with vacuum ultraviolet light.
Wilson, Kevin R.   +2 more
core   +1 more source

Kinetic Isotope Effect in the Unfolding of a Protein Secondary Structure: Calculations for Beta-Sheet Polyglycine Dimers as a Model

open access: yesBiomolecules
In the present work, we performed calculations of the kinetic isotope effect (KIE) on H/D, 14N/15N, 16O/18O, and 12C/13C isotopic substitution in the dissociation of beta-sheet polyglycine dimers of different lengths into two monomer chains.
Alexey O. Yanshin   +2 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Principles of chemical kinetics

open access: yes, 2007
James House's revised Principles of Chemical Kinetics provides a clear and logical description of chemical kinetics in a manner unlike any other book of its kind.
House, James E
core  

Optimization and Evaluation of Drying Kinetics and Quality Attributes of Persimmon Using Infrared Dryer: Influence of Operational Parameters [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering
The impact of infrared drying parameters on drying time and the qualitative characteristics of the persimmon was thoroughly investigated by varying sample thickness (3, 5, and 7 mm), air velocity (0.5, 1.25, and 2 m/s), and infrared power levels (1000 ...
Hasan Jamal Debaklou   +2 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

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