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Artificial Lipid Membranes: Past, Present, and Future
The multifaceted role of biological membranes prompted early the development of artificial lipid-based models with a primary view of reconstituting the natural functions in vitro so as to study and exploit chemoreception for sensor engineering.
Christina G. Siontorou +3 more
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Protective Function of Lipid Rafts [PDF]
The study of lipid rafts allowed us to take a new look at the morphology, organization and functioning of membranes, both of animal and plant origin.
I.S. Kapustina +4 more
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Preparation of artificial plasma membrane mimicking vesicles with lipid asymmetry. [PDF]
Lipid asymmetry, the difference in lipid distribution across the lipid bilayer, is one of the most important features of eukaryotic cellular membranes.
Qingqing Lin, Erwin London
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The lipid membranes of living cells are composed of a large number of lipid types and can undergo phase separation with the formation of nanometer-scale liquid-ordered lipid domains, also called rafts. Raft coalescence, i.e., the fusion of lipid domains,
Konstantin V. Pinigin, Sergey A. Akimov
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Cell membranes are very complex biological systems including a large variety of lipids and proteins. Therefore, they are difficult to extract and directly investigate with biophysical methods.
Alessandra Luchini, Giuseppe Vitiello
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Early cell membrane models placed most proteins external to lipid bilayers in trimolecular structures or as modular lipoprotein units. These thermodynamically untenable structures did not allow lipid lateral movements independent of membrane proteins ...
Garth L. Nicolson +1 more
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Lipid asymmetry, the difference in the lipid composition in the inner and outer lipid monolayers (leaflets) of a membrane, is an important feature of eukaryotic plasma membranes.
Erwin London
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Lipid Transporters Beam Signals from Cell Membranes
Lipid composition in cellular membranes plays an important role in maintaining the structural integrity of cells and in regulating cellular signaling that controls functions of both membrane-anchored and cytoplasmic proteins.
Miliça Ristovski +3 more
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Membrane Heterogeneity Beyond the Plasma Membrane
The structure and organization of cellular membranes have received intense interest, particularly in investigations of the raft hypothesis. The vast majority of these investigations have focused on the plasma membrane of mammalian cells, yielding ...
Hong-Yin Wang +3 more
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The effects of molecular and nanoscopic additives on phospholipid membranes
Lipid bilayers—the main matrix of cell membranes—are a paradigm of soft molecular assemblies whose properties have been evolutionarily optimized to satisfy the functional requirements of cells.
Teshani Kumarage +5 more
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