Results 71 to 80 of about 463,207 (305)

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Kinetics of chemical processes

open access: yes, 1991
Kinetics of Chemical Processes details the concepts associated with the kinetic study of the chemical processes.
Boudart, Michel
core  

Ammonia/Ethane Blends Combustion and Oxidation: Experimental and Numerical Study

open access: yesApplied Sciences
Ammonia is considered as a promising hydrogen carrier and a carbon-free fuel. Methods for improving ammonia combustion characteristics often involve its co-firing with more reactive fuels (natural gas, biofuels, etc.).
Ksenia N. Osipova   +4 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Reaction kinetics for chemical engineers

open access: yes, 1989
Reaction Kinetics for Chemical ...
Walas, Stanley M.
core  

Fuel-Rich Premixed n-Heptane/Toluene Flame: a Molecular Beam Mass Spectrometry and Chemical Kinetic Study

open access: yesEurasian Chemico-Technological Journal, 2014
The mole fraction profiles of major flame species and intermediates including PAH precursors are measured in an atmospheric premixed burner-stabilized fuel-rich (φ = 1.75) n-heptane/toluene/O2/Ar flame (n-heptane/toluene ratio is 7:3 by liquid volume ...
D. A. Knyazkov   +5 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Kinetics of Chemical Reactions

open access: yes, 2023
This course deals with the experimental and theoretical aspects of chemical reaction kinetics, including transition-state theories, molecular beam scattering, classical techniques, quantum and statistical mechanical estimation of rate constants, pressure-
Green Jr., William, Steinfeld, Jeffrey
core  

Flow-distributed spikes for Schnakenberg kinetics [PDF]

open access: yes, 2011
This is the post-print version of the final published paper. The final publication is available at link.springer.com by following the link below. Copyright @ 2011 Springer-Verlag.We study a system of reaction–diffusion–convection equations which combine ...
Winter, M   +3 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

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