Results 61 to 70 of about 6,332,632 (254)

Swelling ability and behaviour of bentonite-based materials for deep repository engineered barrier systems: Influence of physical, chemical and thermal factors

Journal of Rock Mechanics and Geotechnical Engineering, 2022
Compacted bentonite–sand (B/S) mixtures have been used as a barrier material in engineered barrier systems (EBSs) of deep geological repositories (DGR) to store nuclear wastes.
Mohammed Alzamel, Mamadou Fall, Sada Haruna   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Combined Effect of Per- and Polyfluoroalkyl Substances, Toxic Metals, Phthalates and Volatile Organic Compounds on Reproductive Hormones

Pollutants
Background: Human exposure to environmental endocrine-disrupting chemicals (EDCs) rarely occurs in isolation, yet most epidemiological research has assessed chemicals individually.
Issah Haruna, Emmanuel Obeng-Gyasi
doaj   +1 more source

Persistent Organic Pollutants and Type 2 Diabetes: A Critical Review of Review Articles

Frontiers in Endocrinology, 2018
Low dose persistent organic pollutants (POPs) have emerged as a new risk for type 2 diabetes (T2D). Despite substantial evidence from human and experimental studies, there are several critical issues which have not been properly addressed by POPs ...
Yu-Mi Lee, David R. Jacobs Jr., Duk-Hee Lee, Duk-Hee Lee   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Commonly co-occurring stressors in industrialized estuaries disrupt larval development in blue mussels

Frontiers in Ocean Sustainability
Recent, substantial declines in blue mussel (Mytilus edulis) beds in northern European estuaries signal an urgent need to unravel how chronic contaminant exposure, climate-driven warming and salinity shifts jointly affect the development and survival of ...
Isabella M. Jackson, Clayton R. Magill, Frances Orton, Mark A. Taggart, Mark G. J. Hartl   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Health and environmental effects of complex chemical mixtures: proceedings [PDF]

, 1985
The Office of Health and Environmental Research (OHER) of the Department of Energy supports a broad long-term research program on human health and environmental effects from potential exposure to energy-related complex chemical mixtures.

core  

Gold-Nanorod-Based Plasmonic Nose for Analysis of Chemical Mixtures

, 2019
We introduce the “plasmonic nose” as a novel approach for detection, recognition, and quantification of mixtures of chemical species. Using a paper substrate and a calligraphy-based fabrication approach, we generated an array of surface-enhanced Raman ...
Huzeyfe Yilmaz (6730307), Zheyu Wang (1463023), Huzeyfe Yilmaz, Baranidharan Raman, Sisi Cao (1402774), Srikanth Singamaneni (1402780), Sisi Cao, Zheyu Wang, Baranidharan Raman (2408737), Sang Hyun Bae, Srikanth Singamaneni, Sang Hyun Bae (6730310)   +11 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source