Results 91 to 100 of about 320,155 (260)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
How Nature Harvests Sunlight: The Physics of Photosynthesis [PDF]
, 2014 Presented on November 3, 2014 at 6:00 p.m. in the Clough Undergraduate Learning Commons, room 144.Klaus J. Schulten received his Diplom degree in physics from the University of Muenster, Germany in 1969, and a Ph.D.
Schulten, Klaus J.
core
How adding a single methylene to dihydrofolate reductase can change its conformational dynamics. [PDF]
J Chem Phys, 2021 Penhallurick RW +3 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
The RED scheme: Rate-constant estimation from pre-steady state weighted ensemble simulations. [PDF]
J Chem Phys, 2021 DeGrave AJ, Bogetti AT, Chong LT.
europepmc +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Three Concepts of Chemical Closure and their Epistemological Significance [PDF]
, 2010 Philosophers have long debated ‘substrate’ and ‘bundle’ theories as to how properties hold together in objects ― but have neglected to consider that every chemical entity is defined by closure of relationships among components ― here designated ‘Closure ...
Earley, Joseph E.
core
Informing NMR experiments with molecular dynamics simulations to characterize the dominant activated state of the KcsA ion channel. [PDF]
J Chem Phys, 2021 Pérez-Conesa S +4 more
europepmc +1 more source
Physical Properties of Chemical Compounds [PDF]
, 1961 Mode of access: Internet.
openaire +2 more sources