Results 51 to 60 of about 1,191,147 (335)

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

Molecular Oncology, EarlyView.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina, Viviana Bazan, Nadia Barraco, Simona Taverna, Mauro Manno, Samuele Raccosta, Anna Paola Carreca, Marco Bono, Tancredi Didier Bazan Russo, Francesco Pepe, Pasquale Pisapia, Lorena Incorvaia, Giuseppe Badalamenti, Giancarlo Troncone, Umberto Malapelle, Daniele Santini, Antonio Russo, Antonio Galvano   +17 more
wiley   +1 more source

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

Molecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam, Salem Chouaib, Mohammad Askandar Iqbal   +2 more
wiley   +1 more source

Guest Editorial: Special Topic on Software for Atomistic Machine Learning [PDF]

The Journal of Chemical Physics 161(6): 060401, 2024
A survey of the contributions to the Journal of Chemical Physics' Special Topic on Software for Atomistic Machine Learning.
arxiv   +1 more source

The QCD phase diagram at nonzero baryon, isospin and strangeness chemical potentials: Results from a hadron resonance gas model [PDF]

Phys.Lett. B605 (2005) 129-136, 2004
We use a hadron resonance gas model to study the QCD phase diagram at nonzero temperature, baryon, isospin and strangeness chemical potentials. We determine the temperature of the transition from the hadronic phase to the quark gluon plasma phase using two different methods.
arxiv   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source

Electrochemically driven regioselective C−H phosphorylation of group 8 metallocenes

Nature Communications, 2022
Metallocene-based phosphines are compounds with potential use in catalysis. Here, the authors report the electrochemical regioselective functionalization of group 8 metallocenes with phosphine oxides; over 60 examples of phosphorylated (benzo)ferrocenes ...
Hao Zheng, Chang-Hui Liu, Shi-Yu Guo, Gu-Cheng He, Xiang-Ting Min, Bo-Chao Zhou, Ding-Wei Ji, Yan-Cheng Hu, Qing-An Chen   +8 more
doaj   +1 more source

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

Molecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas, Konstantinos Voutetakis, Vivian Kosmidou, Spyridon Tsikalakis, Spyridon Roditis, Konstantinos Pateas, Ryangguk Kim, Kymberleigh Pagel, Stephan Wolf, Gregor Warsow, Antonia Dimitrakopoulou‐Strauss, Georgios N. Zografos, Alexander Pintzas, Johannes Betge, Olga Papadodima, Stefan Wiemann   +15 more
wiley   +1 more source

State-of-the-Art Functional Biomaterials in China

Journal of Functional Biomaterials
In recent years, rapid advancements in multidisciplinary fields (materials, biology, chemical physics, etc [...]
Yuqin Qiao, Huiliang Cao
doaj   +1 more source

Negative magnetoresistance without well-defined chirality in the Weyl semimetal TaP

Nature Communications, 2016
Magnetoresistance of topological semimetal shows unusual electron transport behaviour. Here, Arnold et al. demonstrate detailed Fermi surface topology of Weyl semimetal TaP and show that negative longitudinal magnetoresistance shows up without well ...
Frank Arnold, Chandra Shekhar, Shu-Chun Wu, Yan Sun, Ricardo Donizeth dos Reis, Nitesh Kumar, Marcel Naumann, Mukkattu O. Ajeesh, Marcus Schmidt, Adolfo G. Grushin, Jens H. Bardarson, Michael Baenitz, Dmitry Sokolov, Horst Borrmann, Michael Nicklas, Claudia Felser, Elena Hassinger, Binghai Yan   +17 more
doaj   +1 more source

Creating enzymes and self-sufficient cells for biosynthesis of the non-natural cofactor nicotinamide cytosine dinucleotide

Nature Communications, 2021
Nicotinamide cytosine dinucleotide is an NAD mimic that can be used to mediate redox reactions. Here the authors design an NCD synthetase for the intracellular production of NCD.
Xueying Wang, Yanbin Feng, Xiaojia Guo, Qian Wang, Siyang Ning, Qing Li, Junting Wang, Lei Wang, Zongbao K. Zhao   +8 more
doaj   +1 more source