Results 51 to 60 of about 320,155 (260)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Effect of location of energy barrier on the product alignment of reaction A+BC [PDF]
, 1996 The trajectory calculations of heavy heavy-light, light light-light, heavy light-light, and light heavy-light mass combination reactions on attractive and repulsive potential surfaces have been carried out to study the dependence of the product ...
Lou, NQ, Han, KL, He, GZ
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Further study on collisional quantum interference effect in energy transfer within CO singlet-triplet mixed states [PDF]
, 1996 In our previous study [G-H Sha, J-B. He, B. Jiang, and C-H. Zhang, J. Chem. Phys. 102, 2772 (1995)], a concept of interference phase angle (theta(ST)) has been formally introduced to define the coherence effect between singlet and triplet energy transfer
Chen, XL +4 more
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FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Introduction to Quantum Algorithms for Physics and Chemistry [PDF]
, 2013 An enormous number of model chemistries are used in computational chemistry to solve or approximately solve the Schr odinger equation; each with their own drawbacks.
Sergio Boixo +9 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Research on bipolar plates at Dalian Institute of Chemical Physics [PDF]
, 2012 Research on bipolar plates at Dalian Institute of Chemical ...
邵志刚
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