Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Temperature, Doping, and Chemical Potential Tuning Intrinsic Defects Concentration in Bi2MoO6: GGA + U Method. [PDF]
ACS Omega, 2023 Wang R, Zhou L, Wang W.
europepmc +1 more source
Absence of sign problem in the (saddle point approximation of the)\n nilpotency expansion of QCD at finite chemical potential [PDF]
, 2010 Sergio Caracciolo, F. Palumbo
openalex +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Reparameterization of the chemical-potential equalization model with DFTB3: A practical balance between accuracy and transferability. [PDF]
J Chem Phys, 2023 Vuong VQ, Cui Q.
europepmc +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Hydrophilic Versus Hydrophobic Coupling in the Pressure Dependence of the Chemical Potential of Alkali Metal and Halide Ions in Water. [PDF]
J Phys Chem B, 2022 Tonti L, Floris FM.
europepmc +1 more source
Chemical and pharmacological investigation of Solanum species of Brazil: a search for solasodine and other potentially useful therapeutic agents [PDF]
, 1991 José Maria Barbosa‐Filho +7 more
openalex +1 more source