Results 71 to 80 of about 4,556,600 (347)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Dynamic simulations of water at constant chemical potential [PDF]
The grand molecular dynamics (GMD) method has been extended and applied to examine the density dependence of the chemical potential of a three-site water model.
Ji, Jie +2 more
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Accepted for publication in the Journal of Statistical Physics. Low-T considerations more extensive. Work of Perdew et al more accurately discussed.
openaire +2 more sources
A new chemical concept: Shape chemical potentials [PDF]
Within the density functional formalism, we introduce the shape chemical potential μin for subsystems, which in the limiting case of point subsystems, is a local chemical potential μn(r). It describes the electron withdrawing/donating ability of specified density fragments. The shape chemical potential does not equalize between subsystems, and provides
Chan, Garnet Kin-Lic, Handy, Nicholas C.
openaire +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Photon Production from a Quark-Gluon-Plasma at Finite Baryon Chemical Potential
We compute the photon production of a QCD plasma at leading order in the strong coupling with a finite baryon chemical potential. Our approach starts from the real time formalism of finite temperature field theory.
C. Itzykson +6 more
core +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The 3-state Potts model as a heavy quark finite density laboratory
The 3-D Z(3) Potts model is a model for finite temperature QCD with heavy quarks. The chemical potential in QCD becomes an external magnetic field in the Potts model.
de Forcrand, Ph. +3 more
core +1 more source
Chemical-potential standard for atomic Bose-Einstein condensates [PDF]
When subject to an external time periodic perturbation of frequency $f$, a Josephson-coupled two-state Bose-Einstein condensate responds with a constant chemical potential difference $\Delta\mu=khf$, where $h$ is Planck's constant and $k$ is an integer ...
Anderson B P +31 more
core +2 more sources

