Results 81 to 90 of about 11,594,512 (293)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Properties of chemically oxidized kininogens.

open access: yesActa Biochimica Polonica, 2003
Kininogens are multifunctional proteins involved in a variety of regulatory processes including the kinin-formation cascade, blood coagulation, fibrynolysis, inhibition of cysteine proteinases etc. A working hypothesis of this work was that the properties of kininogens may be altered by oxidation of their methionine residues by reactive oxygen species ...
Niziołek-Kierecka, Magdalena   +4 more
openaire   +4 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Chemical Literature

open access: yes, 1959
Quarterly supplement for "the regular journals of the American Chemical Society," containing annotated bibliographies of chemical documentation literature as well as information about meetings, conferences, awards, scholarships, and other news from the ...
American Chemical Society. Division of Chemical Literature.   +1 more
core  

Carbon Nanofibers Grown on Large Woven Cloths: Morphology and Properties of Growth

open access: yesC, 2016
The morphology and chemical composition of carbon nanofibers in situ grown on a large carbon-fiber woven fabric are studied using SEM measurements, X-ray Diffraction, X-ray Flourescence, and X-ray Photoelectron Spectroscopy.
Vitaly Koissin   +5 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Determinación de la sostenibilidad de la industria mineral de la cerámica y del vidrio mediante herramientas de gestión ambiental

open access: yesBoletín de la Sociedad Española de Cerámica y Vidrio, 2011
In the last few years we have seen the creation of an everyday larger and varied series of are creating large and varied series of environmental management tools used to analyze and classify environmentally each mineral and its physical, economic and ...
Espí Rodriguez, J. A.
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Chemical Literature

open access: yes, 1974
Quarterly supplement for "the regular journals of the American Chemical Society," containing annotated bibliographies of chemical documentation literature as well as information about meetings, conferences, awards, scholarships, and other news from the ...
American Chemical Society. Division of Chemical Literature.   +1 more
core   +1 more source

SYNTHESIS AND CHEMICAL PROPERTIES OF DIHYDROTHIAMINE

open access: yesTHE JOURNAL OF VITAMINOLOGY, 1955
Synthesis of dihydrothiamine (II), mp 150°, from 2-methyl-4-amino-5-aminomethyl-pyrlmldine (IV), γ-aceto-γ-mercapto-propyl alcohol (V) and formaldehyde was described. Treatment of dihydrothiamine with sodium hydroxide yielded isodlhydrothlamine, mp 160°, and both dihydrothiamine and isodihydrothiamine, when dissolved in water, were converted into ...
MATSUKAWA, TAIZO, IWATSU, TAKEO
openaire   +3 more sources

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