Results 41 to 50 of about 1,192,891 (278)

Force and Motion Generation of Molecular Motors: A Generic Description [PDF]

, 1999
We review the properties of biological motor proteins which move along linear filaments that are polar and periodic. The physics of the operation of such motors can be described by simple stochastic models which are coupled to a chemical reaction.
A. Ajdari, A. Ishijima, A.F. Huxley, A.F. Huxley, A.J. Hunt, B. Alberts, C. Shingyoji, C.R. Doering, C.S. Peskin, C.S. Peskin, D. Riveline, D.A. Winkelmann, E. Mandelkow, F. Jülicher, F. Jülicher, F. Jülicher, F.J. Nédélec, H. Fujita, H. Risken, H.E. Huxley, I. Derényi, I.R. Gibbons, J. Prost, J. Rousselet, J.A. Spudich, J.F. Chauwin, J.F. Chauwin, J.T. Finer, J.W.S. Pringle, K Svoboda, K. Svoboda, K. Yasuda, K.A.P. Edman, L. Gorre, L. Gorre-Talini, L.P. Faucheux, M. Büttiker, M. Schnitzer, M.O. Magnasco, P. Reimann, R. Landauer, R.D. Astumian, R.D. Astumian, R.P. Feynman, R.W. Lymn, S. Camalet, S. Leibler, S.J. Kron, S.M. Block, S.P. Gilbert, T. Duke, T. Kreis, T.L. Hill, Y. Harada, Y. Okada   +54 more
core   +3 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Chemical dynamics of triacetylene formation and implications to the synthesis of polyynes in Titan's atmosphere [PDF]

, 2009
For the last four decades, the role of polyynes such as diacetylene (HCCCCH) and triacetylene (HCCCCCCH) in the chemical evolution of the atmosphere of Saturn's moon Titan has been a subject of vigorous research. These polyacetylenes are thought to serve
A. M. Mebel, Gladstone, Gu, Guo, Jones, Kislov, Landera, Lorenz, M. C. Liang, Porco, R. I. Kaiser, Waite, X. Gu, Y. L. Yung, Y. S. Kim   +14 more
core   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Computational models for inferring biochemical networks [PDF]

, 2014
Biochemical networks are of great practical importance. The interaction of biological compounds in cells has been enforced to a proper understanding by the numerous bioinformatics projects, which contributed to a vast amount of biological information ...
Crina Grosan, D Voet, David Gilbert, E Aarts, G Fogel, I Swameye, J Kitagawa, JT Heaton, K Yeung, K Yeung, M Heiner, M Oltean, M Oltean, Ovidiu Parvu, R Breitling, Ramona Stoica, S Kirkpatrick, Silvia Rausanu, U Klingmueller, W Elliot, Zujian Wu   +20 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Modeling the Impact of Moderate External UV Irradiation on Disk Chemistry

The Astrophysical Journal
The chemistry within a protoplanetary disk is greatly affected by external radiation from the local stellar environment. Previous work has focused on extreme radiation fields, representative of the center of something like the Orion Nebula Cluster ...
Rachel E. Gross, L. Ilsedore Cleeves
doaj   +1 more source

An algebraic method to calculate parameter regions for constrained steady-state distribution in stochastic reaction networks

, 2018
Steady state is an essential concept in reaction networks. Its stability reflects fundamental characteristics of several biological phenomena such as cellular signal transduction and gene expression.
Hasegawa, Yoshihiko, Van Vu, Tan
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Evaluation of Chemical Equilibrium and Non-Equilibrium Properties for LOX/LH2 Reaction Schemes

Journal of Aerospace Technology and Management, 2015
Nine chemical reaction models for equilibrium schemes and six chemical models for non-equilibrium ones are studied, considering different conditions found in real liquid oxygen/liquid hydrogen rocket engines.
Carlos Henrique Marchi, Luciano Kiyoshi Araki   +1 more
doaj