Results 51 to 60 of about 1,196,417 (299)

The Pisa Stellar Evolution Data Base for low-mass stars

, 2012
The last decade showed an impressive observational effort from the photometric and spectroscopic point of view for ancient stellar clusters in our Galaxy and beyond.
Degl'Innocenti, S., Dell'Omodarme, M., Moroni, P. G. Prada, Valle, G.   +3 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The interstellar gas-phase chemistry of HCN and HNC

, 2014
We review the reactions involving HCN and HNC in dark molecular clouds to elucidate new chemical sources and sinks of these isomers. We find that the most important reactions for the HCN-HNC system are Dissociative Recombination (DR) reactions of HCNH ...
Hickson, Kevin M., Loison, Jean-Christophe, Wakelam, Valentine   +2 more
core   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Chemical knowledge-informed framework for privacy-aware retrosynthesis learning

Nature Communications
Chemical reaction data is a pivotal asset, driving advances in competitive fields such as pharmaceuticals, materials science, and industrial chemistry.
Guikun Chen, Xu Zhang, Xiaolin Hu, Yong Liu, Yi Yang, Wenguan Wang   +5 more
doaj   +1 more source

Evaluation of in-situ shrinkage and expansion properties of polymer composite materials for adhesive anchor systems by a novel approach based on digital image correlation [PDF]

, 2019
The curing reaction of thermosetting resins is associated with chemical shrinkage which is overlapped with thermal expansion as a result of the exothermal enthalpy. Final material properties of the polymer are determined by this critical process.
Lichtenegger, Helga C., Singer, Gerald, Sinn, Gerhard, Veigel, Stefan, Wan-Wendner, Roman, Zecchini, Michele   +5 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

ReactionT5: a pre-trained transformer model for accurate chemical reaction prediction with limited data

Journal of Cheminformatics
Accurate chemical reaction prediction is critical for reducing both cost and time in drug development. This study introduces ReactionT5, a transformer-based chemical reaction foundation model pre-trained on the Open Reaction Database—a large publicly ...
Tatsuya Sagawa, Ryosuke Kojima
doaj   +1 more source

Computational models for inferring biochemical networks [PDF]

, 2014
Biochemical networks are of great practical importance. The interaction of biological compounds in cells has been enforced to a proper understanding by the numerous bioinformatics projects, which contributed to a vast amount of biological information ...
Crina Grosan, D Voet, David Gilbert, E Aarts, G Fogel, I Swameye, J Kitagawa, JT Heaton, K Yeung, K Yeung, M Heiner, M Oltean, M Oltean, Ovidiu Parvu, R Breitling, Ramona Stoica, S Kirkpatrick, Silvia Rausanu, U Klingmueller, W Elliot, Zujian Wu   +20 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source