Results 71 to 80 of about 669,188 (305)
Constructing and visualizing chemical reaction networks from pi-calculus models [PDF]
Formal Aspects of Computing, 2013 Abstract The π -calculus, in particular its stochastic version the stochastic π -calculus, is a common modeling formalism to concisely describe the chemical reactions occurring in biochemical systems.
John, M. +4 more
openaire +5 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
PLoS ONE, 2012 The inference of reaction rate parameters in biochemical network models from time series concentration data is a central task in computational systems biology.
Philipp Kügler
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Disentangling CO Chemistry in a Protoplanetary Disk Using Explanatory Machine-learning Techniques
The Astrophysical JournalMolecular abundances in protoplanetary disks are highly sensitive to the local physical conditions, including gas temperature, gas density, radiation field, and dust properties.
Amina Diop +4 more
doaj +1 more source
Hierarchical Harmonization of Atom-Resolved Metabolic Reactions across Metabolic Databases
Metabolites, 2021 Metabolic models have been proven to be useful tools in system biology and have been successfully applied to various research fields in a wide range of organisms.
Huan Jin, Hunter N. B. Moseley
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
The Astronomical JournalThe chemical composition of protoplanetary disks, especially in the molecular layer and above, is set by photoprocesses driven by stellar radiation fields.
Jamila Pegues +5 more
doaj +1 more source
, 2016 Recent research in both the experimental and mathematical communities has focused on biochemical interaction systems that satisfy an "absolute concentration robustness" (ACR) property.
Anderson, David F. +2 more
core +1 more source
Analytical Formulas of Molecular Ion Abundances and N2H+ Ring in Protoplanetary Disks [PDF]
, 2015 We investigate the chemistry of ion molecules in protoplanetary disks, motivated by the detection of N$_2$H$^+$ ring around TW Hya. While the ring inner radius coincides with the CO snow line, it is not apparent why N$_2$H$^+$ is abundant outside the CO ...
Aikawa, Yuri +3 more
core +3 more sources