Results 51 to 60 of about 6,987,585 (297)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Designing covalent organic frameworks with Co-O4 atomic sites for efficient CO2 photoreduction

Nature Communications, 2023
A class of inexpensive aminoanthraquinone organic dyes are shown to facilitate visible-light-driven CO2 reduction. Overall reaction efficiencies were found to be optimal when both electron donating and accepting groups were on a single dye molecule.
Qian Zhang, Shuaiqi Gao, Yingying Guo, Huiyong Wang, Jishi Wei, Xiaofang Su, Hucheng Zhang, Zhimin Liu, Jianji Wang   +8 more
doaj   +1 more source

Copper-catalyzed oxidative dehydrogenative dearomatization of indole derivatives: A new strategy to construct spirocyclic indolenines

iScience, 2022
Summary: A concise copper-catalyzed oxidative dehydrogenative dearomatization of indole derivatives for the direct synthesis of spirocyclic indolenines containing fluorene and indeno[2,1-b]indole groups has been established.
Junli Chao, Yuanyuan Yue, Ke Wang, Xiaohui Guo, Chunying Sun, Yue Xu, Jianming Liu   +6 more
doaj   +1 more source

Programmability of Chemical Reaction Networks [PDF]

, 2009
Motivated by the intriguing complexity of biochemical circuitry within individual cells we study Stochastic Chemical Reaction Networks (SCRNs), a formal model that considers a set of chemical reactions acting on a finite number of molecules in a well-stirred solution according to standard chemical kinetics equations.
Matthew Cook 0001, David Soloveichik, Erik Winfree, Jehoshua Bruck   +3 more
openaire   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Crystal structure of 5-(2,6-dimethyl-4H-pyran-4-ylidene)-1,3-dimethylpyrimidine- 2,4,6(1H,3H,5H)-trione, C13H14N2O4

Zeitschrift für Kristallographie - New Crystal Structures, 2013
C13H14N2O4, orthorhombic, Pna21 (no. 33), a = 15.85(2) Å, b = 4.318(5) Å, c = 17.42(2) Å, V = 1191.9 Å3, Z = 4, Rgt(F) = 0.0823, wRref(F2) = 0.2340, T = 296 K.
Li Xiaochuan, Li Yajuan, Zhang Junna, Son Young-A   +3 more
doaj   +1 more source

Siphons in Chemical Reaction Networks [PDF]

Bulletin of Mathematical Biology, 2010
Siphons in a chemical reaction system are subsets of the species that have the potential of being absent in a steady state. We present a characterization of minimal siphons in terms of primary decomposition of binomial ideals, we explore the underlying geometry, and we demonstrate the effective computation of siphons using computer algebra software ...
Shiu, Anne, Sturmfels, Bernd
openaire   +6 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Crystal structure of 2,6-diiodo-8-(3-iodophenyl)-phenyl-BODIPY, C19H16BF2I3N2

Zeitschrift für Kristallographie - New Crystal Structures, 2013
C19H16BF2I3N2, triclinic, P1̄ (no. 2), a = 10.163(1) Å, b = 10.682(1) Å, c = 11.592(1) Å, α = 63.658(1)°, β = 79.529(3)°, γ = 72.106(2)°, V = 1071.6 Å3, Z = 2, Rgt(F) = 0.0306, wRref(F2) = 0.0721, T = 296 K.
Li Xiaochuan, Jiang Wenjuan, Li Yajuan, Zhang Junna, Son Young-A   +4 more
doaj   +1 more source

Quantitative Nanomechanical Mapping of Polyolefin Elastomer at Nanoscale with Atomic Force Microscopy

Nanoscale Research Letters, 2021
Elastomeric nanostructures are normally expected to fulfill an explicit mechanical role and therefore their mechanical properties are pivotal to affect material performance.
Shuting Zhang, Yihui Weng, Chunhua Ma
doaj   +1 more source