Results 71 to 80 of about 6,987,585 (297)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Information extraction from chemical patents [PDF]
, 2011 The automated extraction of semantic chemical data from the existing literature is demonstrated. For reasons of copyright, the work is focused on the patent literature, though the methods are expected to apply equally to other areas of the chemical ...
core +4 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Surficial Functionalization of Monolithic Carbon Electrode via Femtosecond Laser Treatment
ChemElectroChemCarbon materials are promising to fulfill the worldwide need for advanced materials in many areas, particularly in electrochemical applications. However, achieving both high conductivity and surface functionalization in carbon electrodes remains a ...
Yuxiao Ding +8 more
doaj +1 more source
International Journal of Electrochemical Science, 2013 The use of fullerene [60] (C60) as carbon support material assists the dispersion of catalysts and provides new ways to develop advanced electrocatalyst materials as a result of its distorted structure.
Zhengyu Bai +7 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Interface-Confined Oxide Nanostructures for Catalytic Oxidation Reactions
, 2013 Heterogeneous catalysts, often consisting of metal nanoparticles supported on high-surface-area oxide solids, are common in industrial chemical reactions.
Bao, Xinhe +4 more
core +1 more source
ChemElectroChemWater electrolysis is a promising route to green hydrogen production, but its operation in chloride‐containing electrolytes (e.g., seawater) is hindered by the competing chlorine evolution reaction (CER) that lowers oxygen evolution reaction (OER ...
Kahyun Ham +4 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source