Development and application of bond cleavage reactions in bioorthogonal chemistry
, 2016 Bioorthogonal chemical reactions are a thriving area of chemical research in recent years as an unprecedented technique to dissect native biological processes through chemistry-enabled strategies. However, current concepts of bioorthogonal chemistry have
Li, Jie, Chen, Peng R.
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Peptides as catalysts for asymmetric 1,4-addition reactions of aldehydes to nitroolefins [PDF]
, 2009 Within this thesis, the development of peptides as highly efficient catalysts for asymmetric conjugate addition reactions of aldehydes to nitroolefins is described.
Wiesner, Markus
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Self-assembled dendrimer polyamide nanofilms with enhanced effective pore area for ion separation
Nature CommunicationsMembrane technology using well-defined pore structure can achieve high ion purity and recovery. However, fine-tuning the inner pore structure of the separation nanofilm to be uniform and enhance the effective pore area is still challenging.
Bingbing Yuan +12 more
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International Journal of Electrochemical Science, 2013 The use of fullerene [60] (C60) as carbon support material assists the dispersion of catalysts and provides new ways to develop advanced electrocatalyst materials as a result of its distorted structure.
Zhengyu Bai +7 more
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Information extraction from chemical patents
, 2011 The automated extraction of semantic chemical data from the existing literature is demonstrated. For reasons of copyright, the work is focused on the patent literature, though the methods are expected to apply equally to other areas of the chemical ...
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Mapping the Space of Chemical Reactions using Attention-Based Neural Networks
, 2020 Organic reactions are usually assigned to classes grouping reactions with similar reagents and mechanisms. Reaction classes facilitate communication of complex concepts and efficient navigation through chemical reaction space.
Alain C., Vaucher +6 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Beads‐on‐string hierarchical structured electrocatalysts for efficient oxygen reduction reaction
Carbon Energy, 2023 Rational design of hierarchically structured electrocatalysts is particularly important for electrocatalytic oxygen reduction reaction (ORR). Here, ZIF‐67 crystals are stringed on core–shell Ag@C nanocables using a coordination‐modulated process.
Yang Yuan +8 more
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Prediction of Chemical Reactions Using Statistical Models of Chemical Knowledge
, 2018 Is chemistry discoverable or can it only be invented? – this is the question of a computer scientist and a philosopher of science when looking at application of artificial intelligence methods for developing new chemical entities and new chemical ...
Philipp-Maximilian, Jacob +1 more
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