Results 61 to 70 of about 6,987,585 (297)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Scientific Reports, 2018 Deep eutectic solvents (DESs), called a new generation of green solvents, have broad applied in synthesis of nanomaterials due to their remarkable physicochemical properties. In this work, we used a unique strategy (adding moderate water (10%) to DES) to
Aoqi Li +5 more
doaj +1 more source
Green Energy & Environment, 2020 Supercapacitors with unique performance have been widely utilized in many fields. Herein, we report a nitrogen and sulfur co-doped graphene aerogel (N/S-GA-2) prepared using a low toxic precursor for high-performance supercapacitors.
Zhiwei Lu +5 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
In Situ Probing of CO2 Reduction on Cu‐Phthalocyanine‐Derived CuxO Complex
Advanced ScienceAn in situ measurement of a CO2 reduction reaction (CO2RR) in Cu‐phthalocyanine (CuPC) molecules adsorbed on an Au(111) surface is performed using electrochemical scanning tunneling microscopy.
Yongchan Jeong +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Prediction of Chemical Reactions Using Statistical Models of Chemical Knowledge [PDF]
, 2018 Is chemistry discoverable or can it only be invented? – this is the question of a computer scientist and a philosopher of science when looking at application of artificial intelligence methods for developing new chemical entities and new chemical ...
Philipp-Maximilian, Jacob +1 more
core +1 more source
Self-assembled dendrimer polyamide nanofilms with enhanced effective pore area for ion separation
Nature CommunicationsMembrane technology using well-defined pore structure can achieve high ion purity and recovery. However, fine-tuning the inner pore structure of the separation nanofilm to be uniform and enhance the effective pore area is still challenging.
Bingbing Yuan +12 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source