Results 81 to 90 of about 6,987,585 (297)
Detection of bond formations by DNA-programmed chemical reactions and PCR amplification
, 2012 A system capable of performing both DNA-templated chemical reactions and detection of bond formations is reported. Photocleavable DNA templates direct reactions.
Zhang, C +7 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Stereodynamics of chemical reactions: quasi-classical, quantum and mixed quantum-classical theories
, 2012 In this review, some benchmark works by Han and coworkers on the stereodynamics of typical chemical reactions, triatomic reactions H + D-2, Cl + H-2 and O + H-2 and polyatomic reaction Cl+CH4/CD4, are presented by using the quasi-classical, quantum and ...
Zhao, Guangjiu, 赵广久, Xu, Wenwu
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Mapping the Space of Chemical Reactions using Attention-Based Neural Networks [PDF]
, 2020 Organic reactions are usually assigned to classes grouping reactions with similar reagents and mechanisms. Reaction classes facilitate communication of complex concepts and efficient navigation through chemical reaction space.
Alain C., Vaucher +6 more
core +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Development and application of bond cleavage reactions in bioorthogonal chemistry
, 2016 Bioorthogonal chemical reactions are a thriving area of chemical research in recent years as an unprecedented technique to dissect native biological processes through chemistry-enabled strategies. However, current concepts of bioorthogonal chemistry have
Li, Jie, Chen, Peng R.
core +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Carbon-driven Chemical Interactions between Alumina and Iron: A possible reaction pathway in Earth's interior [PDF]
, 2008 Seismological and geochemical observations have revealed a complex structure for the earth's core-mantle boundary (CMB) region, with lateral and chemical heterogeneities.
Rita Khanna +2 more
core
, 2005 In this article, we describe an apparatus in our laboratory for investigating elementary chemical reactions using the high resolution time-of-flight Rydberg tagging method.
Ren, ZF +6 more
core +1 more source