Results 91 to 100 of about 919,666 (317)

Molecular Complexity for Chemical Reactions

open access: yes, 2023
A new method is presented on how to calculate molecular complexity for chemical reactions by the fractal dimension of educts and products. Two pathways for the total synthesis of strychnine were compared.
Sander, Thomas   +3 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Carbon-driven Chemical Interactions between Alumina and Iron: A possible reaction pathway in Earth's interior

open access: yes, 2008
Seismological and geochemical observations have revealed a complex structure for the earth's core-mantle boundary (CMB) region, with lateral and chemical heterogeneities.
Rita Khanna   +2 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1429-1452, June 2026.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Graphene‐Based Phthalocyanine‐Assembled Synergistic Fe‐Co‐Ni Trimetallic Single‐Atomic Bifunctional Electrocatalysts by Rational Design for Boosting Oxygen Reduction/Evolution Reactions

open access: yesCarbon Energy
Development of high‐efficiency bifunctional oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) electrocatalysts is vital for the widespread application of zinc–air batteries (ZABs).
Yujun Wu   +9 more
doaj   +1 more source

Observing the stereodynamics of chemical reactions using randomly oriented molecular beams

open access: yes, 2006
A new method is demonstrated to study the stereodynamics of simple chemical reactions that does not require the use of oriented (or aligned) molecular beams or measurements of the orientation state of product molecules.
Harich, SA   +8 more
core   +1 more source

On new Chemical Reactions of Polymers [PDF]

open access: yesPure and Applied Chemistry, 1968
Abstract
openaire   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1398-1419, June 2026.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Chemical boundary layers in CVD II. Reversible reactions [PDF]

open access: yes, 1990
In addition to irreversible reactions, which were treated in part I, reversible reactions in the gas phase have beenstudied using the concept of the chemical boundary layer.
Croon, de, M.H.J.M., Giling, L.J.
core   +1 more source

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