Results 91 to 100 of about 919,666 (317)
Molecular Complexity for Chemical Reactions
A new method is presented on how to calculate molecular complexity for chemical reactions by the fractal dimension of educts and products. Two pathways for the total synthesis of strychnine were compared.
Sander, Thomas +3 more
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Seismological and geochemical observations have revealed a complex structure for the earth's core-mantle boundary (CMB) region, with lateral and chemical heterogeneities.
Rita Khanna +2 more
core
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Development of high‐efficiency bifunctional oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) electrocatalysts is vital for the widespread application of zinc–air batteries (ZABs).
Yujun Wu +9 more
doaj +1 more source
Observing the stereodynamics of chemical reactions using randomly oriented molecular beams
A new method is demonstrated to study the stereodynamics of simple chemical reactions that does not require the use of oriented (or aligned) molecular beams or measurements of the orientation state of product molecules.
Harich, SA +8 more
core +1 more source
On new Chemical Reactions of Polymers [PDF]
Abstract
openaire +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Chemical boundary layers in CVD II. Reversible reactions [PDF]
In addition to irreversible reactions, which were treated in part I, reversible reactions in the gas phase have beenstudied using the concept of the chemical boundary layer.
Croon, de, M.H.J.M., Giling, L.J.
core +1 more source

