Results 71 to 80 of about 1,559,834 (252)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Women in chemistry: Q&A with Dr Laura Cattaneo
Communications ChemistryDr Laura Cattaneo is a group leader at the Max Planck Institute for Nuclear Physics in Heidelberg, Germany. She has an interdisciplinary research background in chemical physics, connecting materials science, liquid crystals, and ultrafast processes in ...
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Methods for verifying the authenticity of hops – an effective tool against falsification
Kvasný průmysl, 2016 Falsifi cation attempts occur in almost all commodities and hops is no exception. It is therefore necessary to look for ways to verify its authenticity.
Jana Olšovská +4 more
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Suitability for Processing of the Fruits of a Promising Candidate Cultivar of Raspberry
Растениевъдни науки, 2014 Chemical composition of fruits of the promising raspberry candidate cultivar No. 60115, developed in the Institute of Mountain Stockbreeding and Agriculture – Troyan was studied.
Diyan Georgiev +3 more
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Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Scientific Reports, 2017 Carbon nanotube/polytetrafluoroethylene composite polymer targets are proposed for use in the fabrication of fluorocarbon thin films using the mid-frequency sputtering process.
Sung Hyun Kim +7 more
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FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Studia Historiae Scientiarum, 2018 The article discusses the issues of implementation of important achievements in the field of metallurgy (including armored weapons, fortifications and the navy), under the supervision of prof.
Mariusz W. Majewski
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