Results 71 to 80 of about 1,417,488 (251)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Highlights In 1941–1945 experts of Research Chemical Institute (RCI RAPW) and Central Military Chemical Test Site (CMCTS) created brand-new samples of chemical protection devices (respirators, protective suits, chemical-warfare decontamination agents ...
A. Yu. Boyko +2 more
doaj +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Women in chemistry: Q&A with Dr Laura Cattaneo
Dr Laura Cattaneo is a group leader at the Max Planck Institute for Nuclear Physics in Heidelberg, Germany. She has an interdisciplinary research background in chemical physics, connecting materials science, liquid crystals, and ultrafast processes in ...
doaj +1 more source
Suitability for Processing of the Fruits of a Promising Candidate Cultivar of Raspberry
Chemical composition of fruits of the promising raspberry candidate cultivar No. 60115, developed in the Institute of Mountain Stockbreeding and Agriculture – Troyan was studied.
Diyan Georgiev +3 more
doaj
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Methods for verifying the authenticity of hops – an effective tool against falsification
Falsifi cation attempts occur in almost all commodities and hops is no exception. It is therefore necessary to look for ways to verify its authenticity.
Jana Olšovská +4 more
doaj
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source

