Results 61 to 70 of about 1,559,834 (252)

Mutation in ribosomal protein S5 leads to spectinomycin resistance in Neisseria gonorrhoeae.

Frontiers in Microbiology, 2013
Spectinomycin remains a useful reserve option for therapy of gonorrhea. The emergence of multidrug-resistant Neisseria gonorrhoeae strains with decreased susceptibility to cefixime and to ceftriaxone makes it the only medicine still effective for ...
Elena eIlina, Maja eMalakhova, Ivan eBodoev, Alla eFilimonova, Nina eOparina, Vadim eGovorun   +5 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Application and research progress of CO₂ capture and utilization technology

Youqicang pingjia yu kaifa
The global consensus on achieving carbon neutrality is driven by the urgent need to address climate change caused by excessive CO2 emissions. Carbon Capture, Utilization, and Storage（CCUS） stands out as a critical solution, receiving significant ...
HE Zhiyong, GUO Benshuai, WANG Dong, MAO Songbai, LI Zhongyu   +4 more
doaj  

Contribution of the 33 Central Scientific Research Test Institute of the Ministry of Defence of the Russian Federation to the Victory over Nazi Germany in the Great Patriotic War

Вестник войск РХБ защиты
Highlights In 1941–1945 experts of Research Chemical Institute (RCI RAPW) and Central Military Chemical Test Site (CMCTS) created brand-new samples of chemical protection devices (respirators, protective suits, chemical-warfare decontamination agents ...
A. Yu. Boyko, V. A. Inozemtcev, V. M. Ryabkin   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Polymer-Assisted In Situ Synthesis of Silver Nanoparticles with Epigallocatechin Gallate (EGCG) Impregnated Wound Patch Potentiate Controlled Inflammatory Responses for Brisk Wound Healing

International Journal of Nanomedicine, 2019
Aditya K Kar,1,2 Amrita Singh,1,2 Nitesh Dhiman,1,2 Mahaveer P Purohit,1,2 Pankaj Jagdale,3 Mohan Kamthan,4 Dhirendra Singh,3 Mahadeo Kumar,3 Debabrata Ghosh,2,5 Satyakam Patnaik1,2 1Water Analysis Laboratory, Nanomaterial Toxicology Group, CSIR-Indian ...
Kar AK, Singh A, Dhiman N, Purohit MP, Jagdale P, Kamthan M, Singh D, Kumar M, Ghosh D, Patnaik S   +9 more
doaj  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Para amino benzoic acid-derived self-assembled biocompatible nanoparticles for efficient delivery of siRNA

International Journal of Nanomedicine, 2015
Teegala Lakshminarayan Reddy,1,5 P Sivarama Krishnarao,2 Garikapati Koteswara Rao,1,5 Eswar Bhimireddy,2 P Venkateswarlu,4 Debendra K Mohapatra,2,5 JS Yadav,2 Utpal Bhadra,3 Manika Pal Bhadra1,5 1Centre for Chemical Biology, CSIR-Indian Institute of ...
Reddy TL, Krishnarao PS, Rao GK, Bhimireddy E, Venkateswarlu P, Mohapatra DK, Yadav JS, Bhadra U, Pal Bhadra M   +8 more
doaj  

Functionalization of MoS2 with 1,2-dithiolanes: toward donor-acceptor nanohybrids for energy conversion

npj 2D Materials and Applications, 2017
Chemical tuning MoS2 for energy applications: Living on the edge MoS2 can be chemically functionalized with organic functional units, to develop innovative hybrid materials suitable for energy conversion.
Ruben Canton-Vitoria, Yuman Sayed-Ahmad-Baraza, Mario Pelaez-Fernandez, Raul Arenal, Carla Bittencourt, Christopher P. Ewels, Nikos Tagmatarchis   +6 more
doaj   +1 more source