Results 111 to 120 of about 575,982 (298)

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

A Simple and Low-Cost Optical Fiber Intensity-Based Configuration for Perfluorinated Compounds in Water Solution

Sensors, 2018
We present a very simple approach for the detection of the Perfluorinated Alkylated Substances (PFAs) in water solution. Perfluorooctanesulfonate (PFOS) and Perfluorooctanoate (PFOA) are the most extensively investigated perfluoroalkyl and ...
Nunzio Cennamo, Girolamo D’Agostino, Filipa Sequeira, Francesco Mattiello, Gianni Porto, Adriano Biasiolo, Rogério Nogueira, Lúcia Bilro, Luigi Zeni   +8 more
doaj   +1 more source

Code-division multiplexed resistive pulse sensor networks for spatio-temporal detection of particles in microfluidic devices

, 2017
Spatial separation of suspended particles based on contrast in their physical or chemical properties forms the basis of various biological assays performed on lab-on-achip devices. To electronically acquire this information, we have recently introduced a
Asmare, Norh, Khodambashi, Roozbeh, Liu, Ruxiu, Sarioglu, A. Fatih, Wang, Ningquan   +4 more
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Development of an e-Nose System for the Early Diagnosis of Sepsis in Mechanically Ventilated Patients: A Preliminary Study

Proceedings
Sepsis is a severe condition and the major cause of mortality in the ICU. Prompt intervention decreases mortality, and non-invasive systems for early diagnosis in ICU patients are necessary.
Stefano Robbiani, Aurora Pierantozzi, Louwrina H. te Nijenhuis, Patricia A. C. Specht, Floor A. Harms, Carmen Bax, Willem van Weteringen, Laura Capelli, Raffaele L. Dellacà   +8 more
doaj   +1 more source

Organic Electrochemical Transistors as Versatile Analytical Potentiometric Sensors

Frontiers in Bioengineering and Biotechnology, 2019
Potentiometric transduction is an important tool of analytical chemistry to record chemical signals, but some constraints in the miniaturization and low-cost fabrication of the reference electrode are a bottleneck in the realization of more-advanced ...
Isacco Gualandi, Marta Tessarolo, Federica Mariani, Domenica Tonelli, Beatrice Fraboni, Erika Scavetta   +5 more
doaj   +1 more source

Dye-free, simultaneous and multianalyte optical recognition using ionic liquid-based polymeric membrane [PDF]

, 2009
The vast majority of chemical sensors are based on a ligand that selectively bind ion of interest. The ligand is typically incorporated within a polymer matrix.
Diamond, Dermot, Kavanagh, Andrew, Radu, Aleksandar   +2 more
core  

Quantitative measurement of combustion gases in harsh environments using NDIR spectroscopy

, 2018
The global climate change calls for a more environmental friendly use of energy and has led to stricter limits and regulations for the emissions of various greenhouse gases.
Bauke, Stephan, Ctistis, Georgios, Golibrzuch, Kai, Müller, Fabian, Niklas, Christian, Wackerbarth, Hainer   +5 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Acoustic Chemical Sensors [PDF]

Science, 1991
B J, Costello, S W, Wenzel, R M, White
openaire   +3 more sources