Results 121 to 130 of about 576,391 (278)

Chemical Sensor Technologies for Sustainable Development: Recent Advances, Classification, and Environmental Monitoring

open access: yesAdvanced Sensor Research
One of the significant issues of concern in recent times is detecting, quantifying, and monitoring various chemical contaminants in the environment. Numerous inorganic and organic substances are discharged into the environment from various anthropogenic ...
Abel Inobeme   +10 more
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Hadron Fluence Measurements with LiF-TLD Sensors at the Proton Synchrotron Accelerator at CERN

open access: yes, 2010
In view of the implementation of beam-monitoring sensors for CERN's Large Hadron Collider (LHC), and also in order to validate Thermoluminescence Detectors as a versatile tool to measure ionizing radiation doses in mixed fields at hadron colliders such ...
Budzanowski, Maciej   +2 more
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Response versus Chain Length of Alkanethiol-Capped Au Nanoparticle Chemiresistive Chemical Vapor Sensors [PDF]

open access: yes, 2010
Au nanoparticles capped with a homologous series of straight chain alkanethiols (containing 4−11 carbons in length) have been investigated as chemiresistive organic vapor sensors.
Brunschwig, Bruce S.   +6 more
core  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Dye-free, simultaneous and multianalyte optical recognition using ionic liquid-based polymeric membrane [PDF]

open access: yes, 2009
The vast majority of chemical sensors are based on a ligand that selectively bind ion of interest. The ligand is typically incorporated within a polymer matrix.
Diamond, Dermot   +2 more
core  

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