Results 141 to 150 of about 158,468 (254)
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Recent Progress in Silver-Ion-Selective Fluorescence Chemical Sensors. [PDF]
Qi Y, Xu H, Chen H.
europepmc +1 more source
Recent Advances in Chemical Sensors Using Porphyrin-Carbon Nanostructure Hybrid Materials. [PDF]
Magna G +7 more
europepmc +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Editorial to the Special Issue "Advances in Optical Biosensors and Chemical Sensors". [PDF]
Esposito F, Campopiano S, Iadicicco A.
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Chemical Sensors and Biosensors for Point-of-Care Testing of Pets: Opportunities for Individualized Diagnostics of Companion Animals. [PDF]
Fonseca WT +6 more
europepmc +1 more source
Recent Advances in (Bio)Chemical Sensors for Food Safety and Quality Based on Silver Nanomaterials. [PDF]
Ivanišević I, Milardović S, Kassal P.
europepmc +1 more source

