Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Triboelectric Nanogenerators as Power Sources for Chemical Sensors and Biosensors. [PDF]
ACS Omega, 2022 Khandelwal G, Deswal S, Dahiya R.
europepmc +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Possibilities of Physical-Chemical Sensors' Use for Optimizing the Processing of Metallurgical Melting Based on Computer Systems. [PDF]
Sensors (Basel), 2023 Ioana A +4 more
europepmc +1 more source
Cantilever-based Resonant Microsensors with Integrated Temperature Modulation for Transient Chemical Analysis [PDF]
, 2015 This work introduces a resonant cantilever platform with integrated temperature modulation for real-time chemical sensing. Embedded heaters allow for rapid thermal cycling of individual sensors, thereby enabling real-time transient signal analysis ...
Brand, Oliver +4 more
core +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
The Frontiers of Functionalized Nanocellulose-Based Composites and Their Application as Chemical Sensors. [PDF]
Polymers (Basel), 2022 Norrrahim MNF +10 more
europepmc +1 more source
Next generation autonomous chemical sensors for environmental monitoring [PDF]
, 2011 Microfluidic technology has great potential to fulfil the increasing demand for environmental monitoring. Through the minimisation of reagents, standard solutions and power consumption, compact autonomous instruments have been developed to perform in ...
Cleary, John +3 more
core +2 more sources
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Chemical sensors for imaging total cellular aliphatic aldehydes in live cells. [PDF]
Chem Sci, 2023 Wills R +5 more
europepmc +1 more source