Results 31 to 40 of about 158,468 (254)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Scientific ReportsChitosan nanosheets (NS) stabilized on poly (3,4-ethylenedioxythiophene): poly(styrene sulfonate) (PEDOT: PSS) was functionalized using Fe3O4 to capacitively remove chloride ions and toxic cadmium ions at optimized pH, concentration, and number of ...
Oluwaseyi D. Saliu +4 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Sensors and “The internet of biochemical things”
Frontiers in Sensors, 2022 In this perspective article, we consider the pathway biochemical sensing will take as the huge businesses underpinning Big Data and the Internet of Things seek new layers of highly valuable information to integrate into our increasingly digitised world ...
Larisa Florea, Dermot Diamond
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Development of a β-Lactoglobulin Sensor Based on SPR for Milk Allergens Detection
Biosensors, 2018 A sensitive and label-free surface plasmon resonance (SPR) based sensor was developed in this work for the detection of milk allergens. β-lactoglobulin (BLG) protein was used as the biomarker for cow milk detection.
Jon Ashley +7 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Single-component-based multicolor emissions enabled by symmetry breaking
Nature CommunicationsExcitation-dependent multicolor emission from a single-component system, independent of aggregation, remains a fundamental challenge due to inherent difficulties in innovative principles.
Simin Lin +9 more
doaj +1 more source
Potentiometric Sensors for Heavy Metals – An Overview
CHIMIA, 2005 An overview of potentiometric sensors that are capable of detecting heavy metal ions is presented. Notwithstanding the tremendous work performed so far, it is obvious that severe limitations still exist in terms of selectivity, limits of ...
Vinod K. Gupta
doaj +1 more source