Results 41 to 50 of about 158,468 (254)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
In recent years, engineered nanostructure assemblies such as nanowire arrays have attracted much research attention due to their unique chemical and functional characteristics collectively. The engineered nano-assemblies usually carry the characteristics
Bo Zhang, Pu-Xian Gao
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The role of chemisorption and physisorption in Fe-doped SnO2 acetone sensors
The gas sensing mechanism is one of the most important parameters of chemiresistive gas sensors, and distinguishing them opens the possibility of manipulating sensor performance. In this study, we introduced the concept of adsorption-type contribution to
Yernar Shynybekov +3 more
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Convenient and effective fabrication of free-standing organic polymer films with tunable properties is highly desirable towards visual sensing applications. Herein, we pioneered an innovative interfacial pyridinium-yne click polymerization strategy to in
Xinyu Gou +9 more
doaj +1 more source
Applications of Graphene-Based Materials in Sensors
This Special Issue compiles a set of innovative developments on the use of graphene-based materials in the fabrication of sensors. In particular, these contributions report original studies on a wide variety of sensors, such as gas sensors for NO2 or NH3
Miguel Hernaez
doaj +1 more source

