Results 181 to 190 of about 4,081,913 (299)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Polymer Informatics Method for Fast and Accurate Prediction of the Glass Transition Temperature from Chemical Structure. [PDF]

Macromolecules
Brierley-Croft S, Olmsted PD, Hine PJ, Mandle RJ, Chaplin A, Grasmeder J, Mattsson J.   +6 more
europepmc   +1 more source

Incorrect Chemical Structure [PDF]

JAMA: The Journal of the American Medical Association, 1980
openaire   +1 more source

Drawing Chemical Structures [PDF]

Chemistry International -- Newsmagazine for IUPAC, 2013
openaire   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

The Effect of Synthesis Conditions and Chemical Structure of Thermoplastic Polyimides on Their Thermomechanical Properties and Short-Term Electrical Strength. [PDF]

Polymers (Basel)
Nazarychev VM, Pavlov AA, Kamalov AM, Borisova ME, Didenko AL, Ivan'kova EM, Kraft VE, Vaganov GV, Nikolaeva AL, Ivanova AS, Lavrentiev VK, Popova EN, Abalov IV, Blokhin AN, Bugrov AN, Kudryavtsev VV.   +15 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Dumpling GNN: Hybrid GNN Enables Better ADC Payload Activity Prediction Based on the Chemical Structure. [PDF]

Int J Mol Sci
Xu S, Xie L, Dai R, Lyu Z.
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Heat-Induced Changes in the Chemical Structure, Hydrophobicity, and Size Distribution of Free/Bound Lipid Transfer Protein 1 and Their Effects on Beer Foam. [PDF]

J Agric Food Chem
Mizuguchi J, Asaka K, Konishi M, Inui T, Uchiyama S, Torisu T.   +5 more
europepmc   +1 more source