Results 131 to 140 of about 1,800,080 (307)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Literature of chemical technology /
, 1968 Based on papers at the 143rd meeting of the American chemical society, Cincinnati, Jan. 13-14, 1963, and the 145th meeting, New York, Sept.
Smith, Julian Francis,1893-1974(viaf)91807956 +1 more
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E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Novel multiphase chemical reaction systems enabled by microfabrication technology
, 2001 Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 2001.Includes bibliographical references (p. 237-251).Advances in MEMS (micro-electromechanical systems) have enabled some of the "Lab-on-a-Chip" technologies and ...
Losey, Matthew W
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Rheology of concentrated protein solutions and attractive colloidal dispersions
, 2018 This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Thesis: Ph. D., Massachusetts Institute of Technology, Department of Chemical Engineering, 2018Cataloged from
Wang, Gang,Ph. D.Massachusetts Institute of Technology.
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Oligonucleotide Technology – A Research Platform for Chemical Biology
CHIMIA, 2001 During the past three decades, considerable progress has been made in the field of oligonucleotide synthesis. Today, oligonucleotides and their derivatives can be prepared by highly optimised, automated procedures. They are used as sophisticated
Robert Häner
doaj
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Chemical science and technology laboratory /
, 1997 "August 1997."Mode of access ...
Chemical Science and Technology Laboratory (U.S.) +1 more
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