Results 131 to 140 of about 1,813,331 (307)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Synthesis of operating procedures for complete chemical plants [PDF]
, 1990 Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1990.Includes bibliographical references (leaves 192-195).by Ramachandran Lakshmanan.Ph ...
Lakshmanan, Ramachandran
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Canadian Society for Chemical Technology [PDF]
The Canadian Society for Chemical Technology (CSCT) is dedicated to "the advancement of chemical technology, the maintenance and improvement of standards of practitioners and educators, and the continual evaluation of chemical technology in Canada ...
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Technology-enhanced learning influence on chemical literacy: A systematic review
Eclética QuímicaChemical literacy is essential to address socio-scientific issues arising today. Technology plays a key role in increasing students’ chemical literacy. Understanding how technology improves chemical literacy can help teachers choose appropriate learning ...
Ananta Ardyansyah, Sri Rahayu
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The Secrets of Memorably Bad Presentations [PDF]
, 2016 Presented on September 7, 2016 from 4-5 p.m. in room G011 of the Molecular Science and Engineering Building.Dr. David Sholl is the ChBE School Chair, Tennenbaum Family Chair and GRA Eminent Scholar for Energy Sustainability at Georgia Institute of ...
Sholl, David S.
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Design and synthesis of polymers for Corona Phase Molecular Recognition (CoPhMoRe) of carbohydrates [PDF]
, 2017 Thesis: Ph. D., Massachusetts Institute of Technology, Department of Chemical Engineering, 2017Cataloged from PDF version of thesis. Page 158 blank.Includes bibliographical references (pages 133-157).The molecular recognition of carbohydrates is ...
Ahn, Jiyoung,Ph.D.Massachusetts Institute of Technology.
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source