Results 31 to 40 of about 1,463,615 (338)

A Probabilistic Chemical Programmable Computer [PDF]

open access: yesarXiv, 2022
The exponential growth of the power of modern digital computers is based upon the miniaturisation of vast nanoscale arrays of electronic switches, but this will be eventually constrained by fabrication limits and power dissipation. Chemical processes have the potential to scale beyond these limits performing computations through chemical reactions, yet
arxiv  

Towards an accelerated decarbonization of chemical industry by electrolysis [PDF]

open access: yesarXiv, 2022
The transition towards carbon-neutral chemical production is challenging due to the fundamental reliance of the chemical sector on petrochemical feedstocks. Electrolysis-based manufacturing, powered by renewables, is a rapidly evolving technology that might be capable of drastically reducing CO2 emissions from the chemical sector.
arxiv  

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

A Series of Plasma Innovation Technologies by Double Glow Discharge Phenomenon [PDF]

open access: yesarXiv, 2020
In order to break the limitation of plasma nitriding technology,which can be applied to a few nonmetallic gaseous elements, the "Double Glow Discharge Phenomenon" was found and then invented the "Double Glow Plasma Surface Metallurgy Technology". This double glow plasma surface metallurgy technology can use any element in the periodic table of chemical
arxiv  

Particle Technology in Chemical Mechanical Planarization

open access: yesKONA Powder and Particle Journal, 2014
In order to keep pace with Moore’s law, multilevel metallization has become the process of choice. Having a planar wafer surface before every successive step in multilevel metallization is important. The Chemical
Kalyan S. Gokhale, Brij M. Moudgil
doaj   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Computational Modeling for the Activation Cycle of G-proteins by G-protein-coupled Receptors [PDF]

open access: yesEPTCS 40, 2010, pp. 39-53, 2010
In this paper, we survey five different computational modeling methods. For comparison, we use the activation cycle of G-proteins that regulate cellular signaling events downstream of G-protein-coupled receptors (GPCRs) as a driving example. Starting from an existing Ordinary Differential Equations (ODEs) model, we implement the G-protein cycle in the ...
arxiv   +1 more source

Chemical analyses in dental adhesive technology

open access: yesJapanese Dental Science Review, 2012
Adhesive technology has evolved rapidly since it was introduced more than fifty years ago. Today, decayed or fractured teeth can be reconstructed minimally invasively and nearly invisibly using adhesive technology.
Yasuhiro Yoshida, Satoshi Inoue
doaj   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

open access: yesFEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung   +6 more
wiley   +1 more source

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