Results 111 to 120 of about 4,956,614 (325)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Transportation engineering for enhanced production of plant natural products in microbial cell factories

Synthetic and Systems Biotechnology
Plant natural products (PNPs) exhibit a wide range of biological activities and have essential applications in various fields such as medicine, agriculture, and flavors.
Yimeng Zuo, Minghui Zhao, Yuanwei Gou, Lei Huang, Zhinan Xu, Jiazhang Lian   +5 more
doaj   +1 more source

Reduced GHG emissions due to compost production and compost use in Egypt [PDF]

, 2010
Composting has been acknowledged as an emission reduction methodology by the UNFCCC. The emission reduction reached by a composting project is determined by comparing the composting scenario with the applicable baseline scenario.
Luske, Boki
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Experimental research on the miscibility law of methanol-product oil blending systems

You-qi chuyun
Objective As an emerging energy source, methanol plays a crucial role in the energy transition. Implementing sequential transportation of methanol through existing product oil pipelines can lower transportation costs and enhance efficiency in the ...
Shangxin ZHAO, Guiliang PANG, Shujuan QIU, Xin HUANG, Lin TENG   +4 more
doaj   +1 more source

Improving Carbon and Process Utilization for Biomass-to-Liquid Fuel Operations [PDF]

, 2013
With the increasing world demand for transportation fuels, declining petroleum reserves and quest for energy security, there is a renewed interest in Fischer-Tropsch (FT) technology as a viable alternative for the production of liquid
James, O. O.
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Chemically Mediated Artificial Electron Transport Chain

ACS Central Science
Electron transport chains (ETCs) are ubiquitous in nearly all living systems. Replicating the complexity and control inherent in these multicomponent systems using ensembles of small molecules opens up promising avenues for molecular therapeutics, catalyst design, and the development of innovative energy conversion and storage systems. Here, we present
Yang, Yu-Dong, Zhang, Qian, Khrouz, Lhoussain, Chau, Calvin, Yang, Jian, Wang, Yuying, Bucher, Christophe, Henkelman, Graeme, Gong, Han-Yuan, Sessler, Jonathan   +9 more
openaire   +4 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

An experimental toolbox for the physical characterization of thermal insulating polymeric foams

Heliyon
Recent advancements in polymer science and manufacturing technologies triggered new developments of porous materials used for mitigating heat losses, such as thermal insulating polymeric foams.
S. Shrestha, Z. Demchuk, F. Polo-Garzon, A. Tamraparni, J. Damron, D. Howard, T. Saito, A.P. Sokolov, D. Hun, C. Gainaru   +9 more
doaj   +1 more source