Results 1 to 10 of about 225,258 (237)

Formulation development and optimization of Lamivudine 300 mg and Tenofovir Disoproxil Fumarate (TDF) 300 mg FDC tablets by D-optimal mixture design

open access: yesHeliyon, 2016
The usage of fixed dose combination (FDC) tablets of Lamivudine and Tenofovir Disoproxil Fumarate (TDF) is increasing due to increased incidences of HIV/Hepatitis B and HIV/TB co-infections.
Prosper Tibalinda   +6 more
doaj   +1 more source

A novel approach to the application of hexagonal mesoporous silica in solid-phase extraction of drugs

open access: yesHeliyon, 2018
Mesoporous silica with hexagonal type structure containing amine functional group was introduced. Firstly, aminopropyl hexagonal mesoporous silica was synthetized in a co-condensation process, via templating route of n-dodecylamine.
Fatemeh Farjadian   +4 more
doaj   +1 more source

Synthesis and synergistic studies of isatin based mixed ligand complexes as potential antifungal therapeutic agents

open access: yesHeliyon, 2019
Metal based drugs are important class of chemotherapeutic agents that have the potential to circumvent drug resistance. Increasing drug resistance, treatment failures and limited treatment options necessitates the development of new therapeutic drugs ...
Ovas Ahmad Dar   +6 more
doaj   +1 more source

Isolation and identification of phenolic antioxidants from Pistacia integerrima gall and their anticholine esterase activities

open access: yesHeliyon, 2018
The galls of Pistacia integerrima are utilized in folk medicines for the treatment of cough, asthma, dysentery, liver disorders and for snake bite. A number of biological active compounds like alkaloids, flavonoids, tannins, saponins and sterols from ...
Muhammad Zahoor   +2 more
doaj   +1 more source

Novel 3-((2-chloroquinolin-3-yl)methylene)indolin-2-one derivatives produce anticancer efficacy in ovarian cancer in vitro

open access: yesHeliyon, 2019
A novel series of 3-((2-chloroquinolin-3-yl)methylene)indolin-2-ones were synthesized, using the ‘molecular hybridization approach’ and evaluated for anticancer efficacy.
Chandrabose Karthikeyan   +7 more
doaj   +1 more source

Silver nanoparticle synthesis by Acalypha wilkesiana extract: phytochemical screening, characterization, influence of operational parameters, and preliminary antibacterial testing

open access: yesHeliyon, 2019
Single pot green synthesis of silver nanoparticles (AgNPs) was successfully carried out using medicinal plant extract of Acalypha wilkesiana via bottom-up approach. Five imperative operational parameters (pH, contact time, concentration, volume ratio and
Adewumi Oluwasogo Dada   +10 more
doaj   +1 more source

Syntheses, physicochemical characterization, antibacterial studies on potassium morpholine dithiocarbamate nickel (II), copper (II) metal complexes and their ligands

open access: yesHeliyon, 2019
Organic molecule dithiocarbamate transition metal complexes are novel and very attractive pharmaceutical targets for the management and control of antibiotic resistant bacteria. The direct reaction has synthesized new transition metal nickel (II), copper
Senthilkumar Balakrishnan   +5 more
doaj   +1 more source

Polyethylene glycol (PEG) decorated graphene oxide nanosheets for controlled release curcumin delivery

open access: yesHeliyon, 2019
Nowadays, the use of nanostructures in various medical and biological fields such as drug delivery in cancer treatment is increasing. Among the nanostructures, graphene oxide (GO) is an excellent candidate for drug delivery application because of its ...
Jalil Charmi   +4 more
doaj   +1 more source

Design, synthesis, biological evaluation and molecular docking studies of novel 3-substituted-5-[(indol-3-yl)methylene]-thiazolidine-2,4-dione derivatives

open access: yesHeliyon, 2018
Various thiazolidine-2,4-dione derivatives 3a-l possessing indole moiety were designed, synthesized using appropriate conventional heating as well as microwave irradiation methods.
K. Srikanth Kumar   +2 more
doaj   +1 more source

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