Results 121 to 130 of about 1,973,105 (333)
Green Chemistry Approaches in Pharmaceutical Synthesis: Sustainable Methods for Drug Development
AppliedChemThe Pharmaceutical Strategy for Europe addresses the environmental implications at all stages of the life cycle of pharmaceuticals, from design and production through use to disposal.
Alina Stefanache +10 more
doaj +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Heliyon, 2019 The present study discusses the isolation of ursolic acid from the chloroform extract of Paulownia tomentosa (Thunb) Steud fruits and its cytotoxic effect has been assessed in-vitro was performed in different cells lines (A-549, MCF-7, HepG2) and in-vivo
Sanaa A. Ali +4 more
doaj +1 more source
Card games are effective tools to enhance foundation year health and safety inductions
FEBS Open Bio, EarlyView.A series of three card games was developed to actively deliver health and safety education to foundation year students. Most students reported positive responses regarding their enjoyment (89.9 %) and learning (74.7 %) from all games evaluated. Data revealed significant improvements in health and safety knowledge (P < 0.0001).
Rumana Rafiq +4 more
wiley +1 more source
Influence of atomic bonds on the properties of the laxative drug sodium picosulphate
Heliyon, 2016 In this work, the influence of the different S═O, S−O, N⋯H, O⋯H, Na⋯O bonds present in the structures of the powerful laxative drug, sodium picosulphate in gas and aqueous solution phases were studied combining the density functional theory (DFT ...
Davide Romani +2 more
doaj +1 more source
Pharmaceutical Chemistry at the ETH Zürich
CHIMIA, 2004 Pharmaceutical Chemistry at the ETH Zürich is devoted to research on structure–activity relationships. The combination of biophysical methods, like protein crystallography, mass spectrometry and NMR, with theoretical approaches such as QSAR studies and molecular mechanical as well as quantum mechanical molecular modeling yield insight into ...
openaire +4 more sources
Recent advances in pharmaceutical sciences IV [PDF]
, 2014 Reproducció del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=234Like in the three previous editions, this E-book compiles a series of contributions in the multidisciplinary research arena of Pharmaceutical Sciences. The E-book has been
Estelrich i Latràs, Joan +2 more
core
FEBS Open Bio, EarlyView.Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani +7 more
wiley +1 more source
Chemistry and Health: A Multidimensional Approach
Sustainable ChemistryThis review explores both the positive and negative impacts of chemistry on society, focusing on the intersection between pharmaceutical, natural, and synthetic chemicals.
Alcione S. de Carvalho +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart +4 more
wiley +1 more source