Results 121 to 130 of about 3,535,364 (294)

UMN Crookston Senior Paige Pitlick Bonds Chemistry with Pharmaceutical Care

open access: yes, 2019
Morthera, Cassandra. (2019). UMN Crookston Senior Paige Pitlick Bonds Chemistry with Pharmaceutical Care.
Morthera, Cassandra
core  

Bio‐Inspired Multifunctional Superhydrophilic Coatings With Remarkably Fast Self‐Healing Abilities

open access: yesAdvanced Functional Materials, EarlyView.
We developed bio‐inspired multifunctional hydrogel‐based coatings that exhibit extremely fast/repeatable self‐healing abilities, long‐lasting anti‐fogging performance, superhydrophilicity in air, and underwater superoleophobicity. By doping multivalent metal‐ions into the hydrogel networks, which promoted hydrogen bonding formation and enhanced the ...
Hyeonjin Kim   +5 more
wiley   +1 more source

Oxygen Evolution Electrocatalysts with Trinuclear, Mixed‐Valence Iron Motifs on Electronically Aligned Carbon Dots

open access: yesAdvanced Functional Materials, EarlyView.
Trinuclear iron oxo‐bridged catalytic ensembles stabilized by aspartic‐acid‐derived carbon dots provide an effective platform for alkaline oxygen evolution. Mixed‐valence charge balancing, inner‐sphere charge transport, and work‐function alignment within the N/O‐rich carbon framework promote cooperative Fe‐site chemistry and efficient OER ...
Megha A. Deshmukh   +13 more
wiley   +1 more source

In Situ Interfacial Assembly of Dynamic Semi‐Interpenetrating Biopolymer Networks for Robust and Mechanically Adaptive Droplet Interfaces

open access: yesAdvanced Functional Materials, EarlyView.
A dynamic interfacial semi‐interpenetrating polymer network is constructed by sequential assembly of β‐sheet‐rich SF and CS‐RL. The SF framework provides mechanical strength, while dynamically associated CS‐RL enables local rearrangement, allowing droplets to rapidly reconfigure without loss of interfacial integrity.
Yaping Zhang   +7 more
wiley   +1 more source

Endosomal Escape of siRNA Polyplexes: A Molecular Dynamics Perspective on Underlying Mechanisms

open access: yesAdvanced Functional Materials, EarlyView.
Molecular dynamics simulations reveal distinct endosomal escape mechanisms of siRNA nanoparticles, ranging from electrostatic membrane attachment to hydrophobic membrane fusion. Hydrophobic residues and anionic endosomal lipids emerge as key determinants of membrane disruption, linking molecular interactions to experimental delivery performance and ...
Katharina M. Steinegger   +5 more
wiley   +1 more source

Membrane fusion as a tool for co-reconstitution of membrane proteins into liposomes

open access: yes, 2015
Department of Chemistry, Biochemistry and Pharmaceutical Sciences (DCBP)DCBP Gruppe Prof.
von Ballmoos, Christoph
core  

Computational study on the mechanism for the synthesis of the active pharmaceutical ingredients nitrofurantoin and dantrolene in both solution and mechanochemical conditions

open access: yes
International audienceComputational chemistry is able to reproduce and explain experimental reaction times for the synthesis of active pharmaceutical ingredients nitrofurantoin and dantrolene both in solution and ball milling ...
Colacino, Evelina   +4 more
core   +1 more source

Integrated Multiband Smart Windows From UV to LWIR Based on Molecularly Engineered Thermochromic Hydrogels

open access: yesAdvanced Functional Materials, EarlyView.
A multiband smart window integrating a thermochromic poly (EEEA‐co‐NIPAM) hydrogel with functional layers, enabling dynamic VIS‐NIR solar modulation alongside UV shielding and low LWIR emissivity. The polymer network forms hydrogen‐bonding interactions, promoting chain collapse above a reduced lower critical solution temperature, and accelerating the ...
Jiashuo Sun   +17 more
wiley   +1 more source

The practice of medicinal chemistry /

open access: yes, 2008
Now in its third edition, this classic reference is the one-stop-shop for information on the foundations of medicinal chemistry for pharmaceutical researchers who are involved in drug development & discovery but who do not have a background in medicinal ...
Wermuth, C. G.
core  

Biomimetic Hybrid‐Membrane Nanoreactor for Deep‐Seated Photodynamic Immunotherapy of Hepatocellular Carcinoma via Dual Catalysis‐Enhanced ROS Amplification and cGAS‐STING Activation

open access: yesAdvanced Functional Materials, EarlyView.
UCNP@MnOx‐Hyp@HRM (UMHM) enables tumor targeting and accumulation. Under 808 nm NIR irradiation, PDT/CDT synergistically triggers ICD and cGAS–STING immunity for deep hepatocellular carcinoma therapy. ABSTRACT Photodynamic therapy (PDT) is promising against hepatocellular carcinoma (HCC).
Wen Li   +10 more
wiley   +1 more source

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