Results 171 to 180 of about 1,924,905 (240)
Correction: Chavda et al. Peptide-Drug Conjugates: A New Hope for Cancer Management. <i>Molecules</i> 2022, <i>27</i>, 7232. [PDF]
Chavda VP+4 more
europepmc +1 more source
This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah+9 more
wiley +1 more source
Green first derivative synchronous spectrofluorimetric determination of lacidipine and its acid degradation product in plasma and mixtures. [PDF]
Attia KAM, Hasan MA, El-Shanawany AM.
europepmc +1 more source
Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases
This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun+9 more
wiley +1 more source
Crystal engineering of pharmaceutical co-crystals from polymorphic active pharmaceutical ingredients [PDF]
Braga, Dario
core
Self‐Assembling Multi‐Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma
A novel modular T‐cell engager platform, MATCH, is developed for personalized multiple myeloma therapy. MATCH uses complementary oligonucleotide‐linked Fab’ fragments to enable flexible targeting of MM antigens and controlled T‐cell activation. The system shows potent, antigen‐specific cytotoxicity in vitro and in vivo, highlighting its potential for ...
Shannuo Li+8 more
wiley +1 more source
<i>Citrus aurantifolia</i> essential oil: antiaging potential through integrated <i>in vitro</i> and <i>in silico</i> studies. [PDF]
Elkhawas YA+6 more
europepmc +1 more source
Despite significant efforts in developing novel biomaterials to regenerate tissue, only a few of them have successfully reached clinical use. It has become clear that the next generation of biomaterials must be multifunctional. Smart biomaterials can respond to environmental or external stimuli, interact in a spatial‐temporal manner, and trigger ...
Sonya Ghanavati+12 more
wiley +1 more source