Results 211 to 220 of about 3,535,364 (294)

Direct upcycling of expired metformin tablets into non-cytotoxic carbon quantum dots. [PDF]

RSC Adv
Kuligowska M, Trębińska-Stryjewska A, Szczęśniak B, Mierczyk Z, Neffe S, Osuchowski ŁP.   +5 more
europepmc   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

Continuous-Flow Synthesis of Antiepileptic Drugs: Process Intensification, Sustainability Metrics, and Scalable Manufacturing. [PDF]

ACS Omega
Upadhyay A, Raj Pandey A, Mishra A, Tewari S.   +3 more
europepmc   +1 more source

Concerted Action of Targeted Nucleic Acid Therapeutics as Flexible, Precision and Personalized Cancer Treatment

Advanced Science, EarlyView.
Combinations of small activating RNAs and small interfering RNAs were developed as personalized precision therapies that simultaneously activate tumor suppressors and silence oncogenes according to the molecular signatures of patient tumors. This combination strategy demonstrated superior anticancer efficacy, highlighting the promise of precision ...
Jing Wu, Jiaxuan Chen, Abdechakour Elkihel, Wenjun Lan, Nicolas Fraunhoffer, Dandan Zhu, Baoping Lian, Christina Galanakou, Zhancun Bian, Xi Liu, Odile Gayet, Loic Moubri, Julie Aglietti Roques, Vikash Reebye, Nagy Habib, Xiaoxuan Liu, Nelson Dusetti, Juan Lucio Iovanna, Ling Peng   +18 more
wiley   +1 more source

The Pharmaceutical Syllabus and Quantitative Pharmaceutical Chemistry

American Journal of Pharmaceutical Education, 1944
openaire   +1 more source

Nickel‐Catalyzed Three‐Component Difluoroalkylation‐Amination for the Direct Access to Anti‐Inflammatory β‐Difluoroalkyl Amines

Advanced Science, EarlyView.
A nickel‐catalyzed three‐component reductive fluoroalkylation‐amination strategy of N‐vinylamides for the direct access to the α‐amidyl‐β‐difluoroalkyl amines was reported here. The synthetic method features with broad substrate scope, mild conditions, high functional group tolerance, and convenience to handle.
Chang Xu, Fangting Ma, Fan Ding, Luyan Wang, Yunxi Li, Yunzhi He, Xingang Zhang, Siyu He, Dandan Liu   +8 more
wiley   +1 more source

Synthesis and diversification of SuFEx-active 2<i>H</i>-indazoles from azobenzenes and ethenesulfonyl fluoride. [PDF]

RSC Adv
Rajaka L, Woo H, Jung M, Jang C, Kim S, Lee J, Kim S, Han S, Bae HY, Han SH.   +9 more
europepmc   +1 more source

Multi‐Scale Bionic Structure Constructs Biomass Flame‐Retardant Thermal Insulation Foam Material

Advanced Science, EarlyView.
Inspired by mussel adhesion and hierarchical brick‐and‐mortar architectures, a cellulose‐based biomimetic foam is constructed by anchoring bentonite nanosheets onto a polydopamine‐decorated cellulose nanofiber network. The resulting foam combines low thermal conductivity with intrinsic flame retardancy and full biodegradability, presenting a ...
Jianming Liao, Lijun Fan, Yunyuan Dong, Xuyu Bao, Xiaobin Chen, Qifu Zheng, Guanqing Zhang, Shen Wang, Wei Chen, Min Zhang, Shuaiming He   +10 more
wiley   +1 more source

Computational applications in secondary metabolite discovery (CAiSMD) 2026: focus on secondary metabolites towards drug discovery. [PDF]

J Cheminform
Ntie-Kang F, Betow JY, Eni DB, Metuge JA, Adriano A, Chama MA, Bamal HD, Kedi PBE, Campos LM, Abdullahi AS, Medina GFF, Mbeket SBN, Adekunle YA, Carvalho ARV, Akamba BDA, Dare CA, Mtulo YB, López-López E, Djoumbou-Feunang Y, Metuge CS, Ndamo S, Shadrack DM, Diallo BN, Bekono BD, Valli M, Mbah JA, Sabiu S, Egieyeh SA, Medina-Franco JL, Ludwig-Müller J.   +29 more
europepmc   +1 more source

Foundation in Basic Chemistry for Pharmaceutical Chemistry

American Journal of Pharmaceutical Education, 1965
openaire   +1 more source