Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair
Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai +18 more
wiley +1 more source
Quantitative Chemistry and Quantitative Pharmaceutical Chemistry
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Global dissemination of tmexCD‐toprJ across bacterial hosts and ecological niches is accompanied by its convergence with blaKPC, blaNDM, and mcr on mobile plasmids. Recombination and acquisition of resistance modules generate distinct multidrug resistant plasmid architectures, facilitating the emergence and spread of high‐risk bacterial populations ...
Kaiwen Song +9 more
wiley +1 more source
RETRACTED: D'Agostino et al. Molecular Mechanisms at the Basis of Pharmaceutical Grade <i>Triticum vulgare</i> Extract Efficacy in Prompting Keratinocytes Healing. <i>Molecules</i> 2020, <i>25</i>, 431. [PDF]
D'Agostino A +5 more
europepmc +1 more source
Qualitative Chemistry and Qualitative Pharmaceutical Chemistry
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A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv +16 more
wiley +1 more source
A novel green synchronous spectrofluorimetric platform for ultra-trace simultaneous determination of letrozole and bicalutamide in pharmaceutical, biological, and environmental matrices. [PDF]
Alrashidi AA, Magdy G, Radwan AS.
europepmc +1 more source
An injectable gelatin‐based tannic acid–iron hydrogel with mild photothermal therapy could not only induce immunogenic cell death, but also elicit ferroptosis of both tumor cells and tumor‐associated macrophages, resulting in DC maturation, T‐cell infiltration and down‐regulation of ferroptosis‐sensitive M2‐type TAMs levels.
Yuan Zhu +10 more
wiley +1 more source
Synthesis and biological evaluation of pyridine-based derivatives as potential inhibitors of <i>Leishmania major</i> propagation. [PDF]
Sabt A +9 more
europepmc +1 more source
Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan +5 more
wiley +1 more source

