Organic Pharmaceutical Chemistry
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Versatile Detection of Cellular Protein via Fluorescence Anisotropy
Cell Lysate Fluorescence Anisotropy (CFAST) utilizes long lifetime dye‐labeled nanobodies for rapid protein quantification in minimally purified, complex cell lysate. When coupled with cellular thermal shift, CFAST allows high‐throughput detection of endogenous protein‐small molecule engagement, facilitating the discovery of novel binders for ...
Qing Tang +12 more
wiley +1 more source
Micellar Enhanced Second Derivative Spectrofluorimetric Determination of Hydrochlorothiazide, Amlodipine, and Telmisartan in Fixed Dose Combination and Spiked Human Plasma. [PDF]
Yenduri S, H S, K NP.
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Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib +8 more
wiley +1 more source
Author Correction: High-throughput discovery of fluoroprobes that recognize amyloid fibril polymorphs. [PDF]
Carroll EC +17 more
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An intelligent Au@CeO2 Hybrid Nanoparticles (ACEF) with microenvironment‐dependent self‐adjustability was engineered to not only perform efficient and tumor‐specific photothermal‐chemodynamic therapy for precise tumor elimination, but also serve as a ROS scavenger in healthy tissues around the tumor to avoid the unexpected oxidative damage and ...
Wenyun Mu +8 more
wiley +1 more source
A vascularized liver‐on‐a‐microsphere system is developed to recreate lobule‐like cellular organization and endothelial barrier function within compartmentalized hydrogel particles. The platform enhances hepatic performance and reveals alanine‐glucose cycle activation linked to improved detoxification capacity, offering a high‐throughput microscale ...
Jingyang Li +9 more
wiley +1 more source
Exploiting Multicomponent Reactions to Drive the Development of Novel Antitubercular Agents: An Overview. [PDF]
Nunes D, Moreira R, Perry MJ, Lopes F.
europepmc +1 more source
Correction: Synthesis, characterization and photocatalytic evaluation of ternary metal-selenide-chitosan microspheres for the degradation of Congo red dye. [PDF]
Khan N +8 more
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Spectrofluorometric and spectrophotometric assay of anticancer drug ensartinib using ion-pair complex formation reaction with eosin Y. [PDF]
Salem H +7 more
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