Results 101 to 110 of about 6,668,546 (356)

A Review on the Bulk and Surface Chemistry of Iron in Atmospherically-relevant Systems Containing Humic Like Substances (HULIS) [PDF]

open access: yes, 2015
As the fourth most abundant element by mass in the Earth’s crust, iron is ubiquitous and its chemistry is rich and interdisciplinary in nature. This review synthesizes the current state of knowledge of iron chemistry in multicomponent atmospheric ...
Al-Abadleh, Hind A.
core   +1 more source

On the stability of nonisothermal Bonnor-Ebert spheres. III. The role of chemistry in core stabilization

open access: yes, 2017
Aims. We investigate the effect of chemistry on the stability of starless cores against gravitational collapse. Methods. We combine chemical and radiative transfer simulations in the context of a modified Bonnor-Ebert sphere to model the effect of ...
Caselli, P., Juvela, M., Sipilä, O.
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Freezing Points Of Aqueous Alcohols: Free Energy Of Interaction Of The CHOH, CH₂, CONH And C[double bond]C Functional Groups In Dilute Aqueous Solutions [PDF]

open access: yes, 1978
The freezing temperatures of dilute aqueous solutions of methanol, ethanol, 2-propanol, butanol, t-butanol, cyclohexanol and ethylene glycol were measured over the concentration range 0.1 to 1 mol kg–1. Osmotic coefficients at 0°C were calculated.
Okamoto, B. Y.   +2 more
core   +1 more source

Library Design in Combinatorial Chemistry by Monte Carlo Methods

open access: yes, 2000
Strategies for searching the space of variables in combinatorial chemistry experiments are presented, and a random energy model of combinatorial chemistry experiments is introduced.
B. M. Cole   +25 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Guanidine Chemistry

open access: yesChemical and Pharmaceutical Bulletin, 2010
Guanidines are categorized as strong organobases; however, their catalytic utility in organic synthesis has not been discussed thoroughly. The author's group has extensively and systematically studied their potential ability focusing on: 1) modified guanidines as chiral auxiliaries; 2) guanidinium ylides for aziridine formation; 3) the affinity of ...
openaire   +3 more sources

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