Results 1 to 10 of about 142,392 (132)

Ultrafast synthesis of α-aminophosphonates using ternary deep eutectic solvent in water [PDF]

Scientific Reports
A remarkably rapid synthesis of α-aminophosphonate medicinally privileged scaffold is developed using a ternary deep eutectic solvent (TDES) of urea/SnCl2/HCl catalyst.
Najmedin Azizi, Navid Habibnejad, Nasim Nourazar, Mehran Shahiri Haghayegh   +3 more
doaj   +2 more sources

Old and Modern Antibiotic Structures with Potential for Today’s Infections

ADMET and DMPK, 2022
Due to the lack of new antibiotics with efficacy against the ESKAPE and other resistant microbes, coupled to the demise of major pharmaceutical company antibiotic discovery programs, due to a number of factors but mainly ROI calculations and the lack of ...
David Newman
doaj   +1 more source

Comparison of the Conventional and Mechanochemical Syntheses of Cyclodextrin Derivatives

Molecules, 2023
Many scientists are working hard to find green alternatives to classical synthetic methods. Today, state-of-the-art ultrasonic and grinding techniques already drive the production of organic compounds on an industrial scale.
László Jicsinszky, Federica Rossi, Roberto Solarino, Giancarlo Cravotto   +3 more
doaj   +1 more source

Early synthetic textile dyes of the late 19th century from the “Primo Levi” Chemistry Museum (Rome): A multi-technique analytical investigation

Journal of Cultural Heritage, 2023
In the present work a historical collection of early synthetic dyes belonging to an Italian museum was investigated through different analytical techniques: Fourier-transform Infrared (FTIR), UV-visible, Raman and surface-enhanced Raman (SERS) spectroscopies, CHN elemental analysis, electron-spray ionization mass spectrometry (ESI-MS) and X-ray ...
Margherita Longoni, Martina Gavazzi, Donato Monti, Silvia Bruni   +3 more
openaire   +3 more sources

Benzo[1,2,3]dithiazole Compounds: A History of Synthesis and Their Renewed Applicability in Materials and Synthetic Chemistry, Originating from the Herz Reaction

Reactions, 2021
The benzo[1,2,3]dithiazole is a unique heteroaromatic functionality whose conjugated profile instils some fascinating electronic properties. This has been historically recognized in the design and manufacture of organic dyes early last century. Although,
Alexander J. Nicholls, Ian R. Baxendale
doaj   +1 more source

Fuelling the Digital Chemistry Revolution with Language Models

CHIMIA, 2023
The RXN for Chemistry project, initiated by IBM Research Europe – Zurich in 2017, aimed to develop a series of digital assets using machine learning techniques to promote the use of data-driven methodologies in synthetic organic chemistry.
Antonio Cardinale, Alessandro Castrogiovanni, Theophile Gaudin, Joppe Geluykens, Teodoro Laino, Matteo Manica, Daniel Probst, Philippe Schwaller, Aleksandros Sobczyk, Alessandra Toniato, Alain C. Vaucher, Heiko Wolf, Federico Zipoli   +12 more
doaj   +1 more source

Development of Advanced Macrosphelides: Potent Anticancer Agents

Molecules, 2015
Synthetic approaches to macrosphelide derivatives, based on medicinal chemistry, are summarized. This review contains conventional medicinal chemistry approaches, combinatorial chemistry, fluorous tagging techniques and affinity chromatography ...
Seung-Mann Paek
doaj   +1 more source

Síntese de cristais líquidos derivados do nitroazobenzeno: uma proposta de síntese multi-etapas aplicada às aulas de química orgânica experimental

Química Nova, 2014
We describe a synthetic route consisting of five steps from aniline to obtain liquid crystal compounds derived from nitroazobenzene. Syntheses were performed during the second half of the semester in organic chemistry laboratory classes.
Rodrigo Cristiano, Marília Gabriela B. Cabral, Rafael B. de Aquino, Cláudia M. Z. Cristiano   +3 more
doaj   +1 more source

Espectroscopia de Ressonância Magnética Nuclear de 13C no estudo de rotas biossintéticas de produtos naturais 13C Nuclear Magnetic Resonance spectroscopy in the studies of biosythetic routes of natural products

Química Nova, 2007
During the last five decades, as a result of an interaction between natural product chemistry, synthetic organic chemistry, molecular biology and spectroscopy, scientists reached an extraordinary level of comprehension about the natural processes by ...
Fernando César de Macedo Júnior
doaj   +1 more source

The green chemistry of chalcones: Valuable sources of privileged core structures for drug discovery

Frontiers in Chemistry, 2022
The sustainable use of resources is essential in all production areas, including pharmaceuticals. However, the aspect of sustainability needs to be taken into consideration not only in the production phase, but during the whole medicinal chemistry drug ...
Ludovica Marotta, Sara Rossi, Roberta Ibba, Simone Brogi, Vincenzo Calderone, Stefania Butini, Giuseppe Campiani, Sandra Gemma   +7 more
doaj   +1 more source