Results 41 to 50 of about 492,973 (270)

Highly efficient methods for the one-pot synthesis of b-substituted enones [PDF]

, 2006
A mild and practically-convenient one-pot procedure for the direct b-substitution of enones has been developed using a conjugate addition–oxidation strategy with a full range of copper-based reagents and N-tert-butylphenylsulfinimidoyl chloride; alkyl ...
Bartoli, Bertz, Colin M. Pearson, Dieter, Endrik, Gilman, Graeme J. Thurston, Hungerford, Jackman, Kozlowski, Lipshutz, Lipshutz, Lipshutz, Lipshutz, Markovskii, Matsuo, Matsuo, Matsuo, Matsuo, Mukaiyama, Mukaiyama, Mukaiyama, Nicolaou, Piers, Piers, Piers, Reich, Reich, Trost, William J. Kerr   +29 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Recent Advances in Indazole-Derived Heterocycles: Synthetic Strategies, Functionalization, and Therapeutic Potential

Journal of Chemistry
Indazole-derived heterocycles have garnered significant attention in recent years due to their versatile chemical structures and wide-ranging biological activities. This review explores the recent progress in the synthesis of indazole-based heterocycles,
Uday V. Bhat, Glanish Jude Martis, Dinesh Chikkanna, Santosh L. Gaonkar   +3 more
doaj   +1 more source

Dendron-Functionalized Surface: Efficient Strategy for Enhancing the Capture of Microvesicles

iScience, 2019
Summary: Microvesicles (MVs) are used by various types of cells in the human body for intercellular communication, making them biomarkers of great potential for the early and non-evasive diagnosis of a spectrum of diseases.
Jian-Qiao Jiang, Christel Chanseau, Isabel D. Alves, Sylvain Nlate, Marie-Christine Durrieu   +4 more
doaj   +1 more source

Covalent Organic Frameworks (COFS): A Review

Journal of Applied Sciences and Environmental Management, 2022
The search for supramolecular promising porous crystalline materials with diverse applications such as gas storage, catalysis, chemo-sensing, energy storage, and optoelectronic have led to the design and construction of Covalent Organic Frameworks (COFs)
O.S. Bull, I. Bull, G.K. Amadi, C.O. Odu   +3 more
doaj   +1 more source

Retrosynthetic reaction prediction using neural sequence-to-sequence models

, 2017
We describe a fully data driven model that learns to perform a retrosynthetic reaction prediction task, which is treated as a sequence-to-sequence mapping problem.
Gomes, Joseph, Ho, Stephen, Kawthekar, Prasad, Liu, Bowen, Nguyen, Quang Luu, Pande, Vijay, Ramsundar, Bharath, Shi, Jade, Sloane, Jack, Wender, Paul   +9 more
core   +2 more sources

Functionalization of Pyrene To Prepare Luminescent Materials—Typical Examples of Synthetic Methodology [PDF]

, 2016
Pyrene-based π-conjugated materials are considered to be an ideal organic electro-luminescence material for application in semiconductor devices, such as organic light-emitting diodes (OLEDs), organic field-effect transistors (OFETs) and organic ...
Ajami, Alfonso, Baldo, Barton, Batsanov, Beaupré, Beller, Bernhardt, Bolm, Cao, Caronna, Caronna, Casas-Solvas, Cerfontain, Chang, Chen, Chen, Cheng, Chercka, Coventry, Crawford, Dewar, Duong, Eliseeva, Espinosa, Feng, Feng, Feng, Feng, Feng, Feng, Feng, Figueira-Duarte, Figueira-Duarte, Figueira-Duarte, Fihri, Fuchibe, Gao, García, Gonell, Grandbois, Hashmi, Hong, Hu, Hu, Hu, Hu, Hu, Hu, Hu, Hu, Hu, Hu, Ibáñez, Inoue, Irvine, Ito, Iwasaki, Jeon, Ji, Ji, Jiang, Jiao, Kamtekar, Katz, Kawano, Keller, Kim, Kim, King, Klauk, Kohl, Kulisic, Kumar, Lambert, Lee, Lee, Letizia, Li, Li, Liu, Malashikhin, Marco, Mateo-Alonso, Miyasaka, Miyaura, Miyaura, Miyazawa, Miyazawa, Mkhalid, Moorthy, More, More, Moulin, Ni, Niko, Oberender, Olah, Olah, Paul, Qiao, Rajca, Rajca, Rathore, Reineke, Schmidt-Mende, Sonar, Sun, Sun, Szaciłowski, Tan, Tanaka, Tang, Tao, Tashiro, Thomas, Trattnig, Trattnig, Valdés, Venkataramana, Verbiest, Verbiest, Visbal, Vollmann, Xiao, Xu, Yamato, Yamato, Yamato, Yamato, Yamato, Yua, Zak, Zhang, Zhang, Zhao, Zwijnenburg, Zöphel, Zöphel, Zöphel   +139 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Anomeric O-Functionalization of Carbohydrates for Chemical Conjugation to Vaccine Constructs. [PDF]

, 2018
Carbohydrates mediate a wide range of biological interactions, and understanding these processes benefits the development of new therapeutics. Isolating sufficient quantities of glycoconjugates from biological samples remains a significant challenge ...
Gervay-Hague, Jacquelyn, Hsieh, Hsiao-Wu, Park, Simon S   +2 more
core   +1 more source

Cavitation in soft matter [PDF]

, 2020
Cavitation is the sudden, unstable expansion of a void or bubble within a liquid or solid subjected to a negative hydrostatic stress. Cavitation rheology is a field emerging from the development of a suite of materials characterization, damage ...
Barney, Christopher W., Cai, Shengqiang, Crosby, Alfred J., Dougan, Carey E., Kazemi-Moridani, Amir, Lee, Jae-Hwang, McLeod, Kelly R., Peyton, Shelly, Riggelman, Robert A., Sacligil, Ipek, Tew, Gregory N., Tiwari, Sacchita, Ye, Ziyu, Zheng, Yue   +13 more
core   +2 more sources